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CD38 抗体

适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 6E12D unconjugated
产品编号 ABIN969023
发货至: 中国
  • 抗原 See all CD38 抗体
    CD38
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    宿主
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    小鼠
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    标记
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    This CD38 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human CD38 expressed in E. coli.
    克隆位点
    6E12D
    亚型
    IgG1
    Top Product
    Discover our top product CD38 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Pavón, Muñoz, Navarro, Raya-Alvarez, Callejas-Rubio, Navarro-Pelayo, Ortego-Centeno, Sancho, Zubiaur: "Increased association of CD38 with lipid rafts in T cells from patients with systemic lupus erythematosus and in activated normal T cells." in: Molecular immunology, Vol. 43, Issue 7, pp. 1029-39, (2005) (PubMed).

    Liu, Verfaillie: "Myeloid-lymphoid initiating cells (ML-IC) are highly enriched in the rhodamine-c-kit(+)CD33(-)CD38(-) fraction of umbilical cord CD34(+) cells." in: Experimental hematology, Vol. 30, Issue 6, pp. 582-9, (2002) (PubMed).

  • 抗原
    CD38
    Abstract
    CD38 产品
    别名
    T10 antibody, Cd38-rs1 antibody, cd38 antibody, ADPRC 1 antibody, cADPr hydrolase 1 antibody, CD38 molecule antibody, CD38 antigen antibody, CD38 molecule L homeolog antibody, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 antibody, CD38 antibody, Cd38 antibody, cd38.L antibody
    背景

    Description: CD38 is a type II integral membrane glycoprotein which is present on early B and T cell lineages and activated B and T cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B cells, mitogen-activated T cells, monocytes and Ig-secreting plasma cells. CD38 acts as a NAD glycohydrolase in T lym- phocytes. On hematopoietic cells CD38 induces activation, proliferation, and differentiation of mature T and B cells and mediates apoptosis of myeloid and lymphoid progenitor cells. In addition to acting as a signaling receptor, CD38 is also an enzyme capable of producing several calcium-mobilizing metabo- lites, including cyclic adenosine diphosphate ribose (cADPR). CD38 also plays a role in maintaining survival of an invariant NK T (iNKT) cell subset that preferentially contributes to the maintenance of immunological tolerance.

    Aliases: T10, CD38

    分子量
    34 kDa
    基因ID
    952
    HGNC
    952
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