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CD28 抗体

This anti-CD28 antibody is a 仓鼠 单克隆 antibody detecting CD28 in FACS. Suitable for 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN135180
发货至: 中国

Quick Overview for CD28 抗体 (ABIN135180)

抗原

See all CD28 抗体
CD28

适用

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小鼠

宿主

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仓鼠

克隆类型

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单克隆

标记

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This CD28 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

37-51
  • 特异性

    Mouse CD28, Mr 40 kDa

    产品特性

    Hamster Anti-Mouse CD28-UNLB

    纯化方法

    Purified

    免疫原

    C57BL/6N mouse T cell lymphoma EL-4 cell line

    亚型

    IgG
  • 应用备注

    • Applications: FC - Quality tested , IP - Reported in literature , Costim - Reported in literature , Stim - Reported in literature , Activ - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    说明

    In vitro costimulation of T cells and NK cells

    样本量

    1 mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

    储存液

    Without preservative

    注意事项

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C
  • Ershaid, Sharon, Doron, Raz, Shani, Cohen, Monteran, Leider-Trejo, Ben-Shmuel, Yassin, Gerlic, Ben-Baruch, Pasmanik-Chor, Apte, Erez: "NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis." in: Nature communications, Vol. 10, Issue 1, pp. 4375, (2020) (PubMed).

  • 抗原

    CD28

    别名

    CD28

    背景

    CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses.

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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