CD11b 抗体
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北京 101111
Quick Overview for CD11b 抗体 (ABIN135134)
抗原
See all CD11b (ITGAM) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Rat Anti-Mouse CD11b-LE/AF
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特异性
- Mouse CD11b, Mr 170 kDa
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产品特性
- Low Endotoxin/Azide Free Anti-Mouse CD11b antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, and blocking assays.
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内毒素水平
- Low Endotoxin
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免疫原
- Peritoneal macrophages from B6D2 hybrid mice
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate buffered saline, pH 7.4
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储存液
- Azide free
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注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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储存条件
- 4 °C
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储存方法
- 2-8°C
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- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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别名
- CD11b
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背景
- CD11b (integrin M subunit) combines with CD18 (integrin 2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.
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基因ID
- 16409
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UniProt
- P05555
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途径
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
抗原
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