CD5 抗体
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北京 101111
Quick Overview for CD5 抗体 (ABIN135112)
抗原
See all CD5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Mouse CD5, Mr 67 kDa
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产品特性
- Rat Anti-Mouse CD5-UNLB
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纯化方法
- Purified
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免疫原
- Unknown
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亚型
- IgG2a
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应用备注
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- Applications: FC - Quality tested
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
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样本量
- 1 mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
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储存液
- Without preservative
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注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C
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- CD5
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别名
- CD5
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背景
- CD5/Lyt-1 antigen is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B-cell antigen CD72. The frequency of CD5+ B cells exhibits strain-dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells. Binding of CD5 on the T cell surface can augment alloantigen- or mitogen-induced lymphocyte proliferation and induces increased cytosolic free calcium, IL-2 secretion, and IL-2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T-cell and B-cell receptors.
抗原
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