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CD5 抗体

This anti-CD5 antibody is a 大鼠 单克隆 antibody detecting CD5 in FACS. Suitable for 小鼠.
产品编号 ABIN135106
发货至: 中国

Quick Overview for CD5 抗体 (ABIN135106)

抗原

See all CD5 抗体
CD5

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD5 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

B19-1
  • 特异性

    Mouse CD5, Mr 67 kDa

    产品特性

    Rat Anti-Mouse CD5-UNLB

    纯化方法

    Purified

    免疫原

    Unknown

    亚型

    IgG2a
  • 应用备注

    • Applications: FC - Quality tested , IP - Reported in literature , WB - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    样本量

    1 mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

    储存液

    Without preservative

    注意事项

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C
  • 抗原

    CD5

    别名

    CD5

    背景

    CD5/Lyt-1 antigen is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B-cell antigen CD72. The frequency of CD5+ B cells exhibits strain-dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells. Binding of CD5 on the T cell surface can augment alloantigen- or mitogen-induced lymphocyte proliferation and induces increased cytosolic free calcium, IL-2 secretion, and IL-2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T-cell and B-cell receptors.
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