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HMGB1 抗体 (AA 1-215)

This anti-HMGB1 antibody is a 小鼠 单克隆 antibody detecting HMGB1 in WB, ELISA, IF 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1326935
发货至: 中国

Quick Overview for HMGB1 抗体 (AA 1-215) (ABIN1326935)

抗原

See all HMGB1 抗体
HMGB1 (High Mobility Group Box 1 (HMGB1))

适用

  • 179
  • 100
  • 100
  • 13
  • 13
  • 13
  • 11
  • 8
  • 7
  • 7
  • 6
  • 6
  • 5
  • 2
  • 1
  • 1
  • 1

宿主

  • 156
  • 47
  • 2
  • 2
  • 2
  • 1
  • 1
小鼠

克隆类型

  • 144
  • 67
单克隆

标记

  • 118
  • 20
  • 20
  • 7
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This HMGB1 antibody is un-conjugated

应用范围

  • 178
  • 81
  • 65
  • 54
  • 47
  • 43
  • 29
  • 27
  • 26
  • 24
  • 9
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

1E6-E10
  • 抗原表位

    • 35
    • 16
    • 16
    • 11
    • 9
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-215

    原理

    Mouse monoclonal antibody raised against a full-length recombinant HMGB1.

    序列

    MGKGDPKKPR GKMSSYAFFV QTCREEHKKK HPDASVNFSE FSKKCSERWK TMSAKEKGKF EDMAKADKAR YEREMKTYIP PKGETKKKFK DPNAPKRPPS AFFLFCSEYR PKIKGEHPGL SIGDVAKKLG EMWNNTAADD KQPYEKKAAK LKEKYEKDIA AYRAKGKPDA AKKGVVKAEK SKKKKEEEED EEDEEDEEEE EDEEDEDEEE DDDDE

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    HMGB1 (AAH03378.1, 1 a.a. ~ 215 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Kim, Ku, Bae: "Persicarin is anti-inflammatory mediator against HMGB1-induced inflammatory responses in HUVECs and in CLP-induced sepsis mice." in: Journal of cellular physiology, Vol. 228, Issue 4, pp. 696-703, (2013) (PubMed).

    Lee, Ku, Kim, Bae: "Emodin-6-O-?-D-glucoside inhibits HMGB1-induced inflammatory responses in vitro and in vivo." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 52, pp. 97-104, (2013) (PubMed).

  • 抗原

    HMGB1 (High Mobility Group Box 1 (HMGB1))

    别名

    HMGB1

    背景

    Full Gene Name: high-mobility group box 1
    Synonyms: DKFZp686A04236,HMG1,HMG3,SBP-1

    基因ID

    3146

    途径

    p53 Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome
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