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DREAM 抗体 (AA 1-256)

This anti-DREAM antibody is a 小鼠 单克隆 antibody detecting DREAM in WB, IHC, ICC 和 IP. Suitable for 大鼠.
产品编号 ABIN1304732
发货至: 中国

Quick Overview for DREAM 抗体 (AA 1-256) (ABIN1304732)

抗原

See all DREAM (KCNIP3) 抗体
DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

适用

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大鼠

宿主

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  • 2
小鼠

克隆类型

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单克隆

标记

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This DREAM antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

克隆位点

K66-38
  • 抗原表位

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    AA 1-256

    特异性

    No off-targets reported for rat KChIPs 1,2, 4

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Description: Our Anti-KChIP3 K+ channel mouse monoclonal primary antibody is produced in-house from hybridoma clone K66/38. It is KO validated, detects human, mouse, and rat KChIP3 K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

    Manufacturer Comment: We produce our KChIP3 K+ channel mouse monoclonal primary antibody from hybridoma clone K66/38. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

    纯化方法

    Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

    纯度

    > 90% specific antibody

    免疫原

    Fusion protein amino acids 1-256 (full length) of rat Calsenillin/DREAM/KChIP3 (accession number Q9JM47) produced recombinantly in E. Coli

    亚型

    IgG2a
  • 应用备注

    Dilution Range: IHC: 1:250

    Dilution Range: ICC: 1:250

    Dilution Range: WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

    储存条件

    4 °C,-20 °C

    储存方法

    Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

    有效期

    24 months
  • 抗原

    DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

    别名

    KChIP3 K+ channel

    背景

    Synonyms: Calsenilin (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3)

    Target Description: Kchip3 potassium channel, also known as Kv channel-interacting protein 3, Kcnip3, DREantagonist modulator and Dream is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin or neuronal calcium sensor (NCS) family branch of the EF-hand superfamily. Kchip3 is an integral subunit component of native Kv4 channel complexes that may regulate A-type currents and function as a calcium regulated transcriptional repressor. Kchip3 is detected in brain, specifically in the cortex, thalamus, dentate gyrus and cerebellum and can be found throughout the cell. It is also found in other tissues at low levels. Diseases associated with KCNIP3 include alzheimer disease.

    Gene Name Alternatives: Kcnip3 Csen Dream Kchip3

    分子量

    34 kDa

    UniProt

    Q9JM47
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