CoREST 抗体 (AA 109-293)
Quick Overview for CoREST 抗体 (AA 109-293) (ABIN1304609)
抗原
See all CoREST (RCOR1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 109-293
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特异性
- No off-targets reported
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Description: Our Anti-Co-Rest/RCOR1 mouse monoclonal primary antibody is produced in-house from hybridoma clone K72/8. It detects human, mouse, and rat Co-Rest/RCOR1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Manufacturer Comment: We produce our Co-Rest/RCOR1 mouse monoclonal primary antibody from hybridoma clone K72/8. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.
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纯度
- > 90% specific antibody
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免疫原
- Fusion protein amino acids 109-293 of human Co-Rest (accession number Q9UKL0), includes ELM2 and SANT domains, produced recombinantly in E. Coli
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 24 months
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- CoREST (RCOR1) (REST Corepressor 1 (RCOR1))
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别名
- RCOR1
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背景
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Synonyms: REST corepressor 1 (Protein CoREST)
Target Description: REST Corepressor 1, CoREST or RCOR is encoded by the gene RCOR1 and is a member of the CoREST family of proteins. CoREST is a corepressor to the RE1 silencing transcription factor/neural restrictive silencing (REST) transcription factor and is part of a multiprotein complex (BHC complex) that represses transcription of neuron-specific genes in non-neuronal cells. This complex determines neural cell differentiation. CoREST is ubiquitously expressed in the nucleus of cells. Diseases associated with this gene include Huntington Disease and Loeys-Dietz Syndrome 1.
Gene Name Alternatives: RCOR1 KIAA0071 RCOR
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分子量
- 66-80 kDa (depending on gel system used)
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NCBI登录号
- NP_055971
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途径
- Regulation of Hormone Metabolic Process, Chromatin Binding
抗原
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