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Lambda-IgLC 抗体 (APC)

Cited in 3+ publications. This APC-conjugated 小鼠 单克隆 anti-Lambda-IgLC antibody (Clone 1-155-2) specifically detects Lambda-IgLC in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN1302655
发货至: 中国
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Quick Overview for Lambda-IgLC 抗体 (APC) (ABIN1302655)

抗原

Lambda-IgLC (lambda Light Chain (Lambda-IgLC))

适用

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宿主

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小鼠

克隆类型

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单克隆

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This Lambda-IgLC antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)

克隆位点

1-155-2
  • 原理

    Anti-Hu Ig Lambda Light Chain APC

    特异性

    The mouse monoclonal antibody 1-155-2 recognizes lambda light chains (22.5 kDa) of human immunoglobulin.

    交叉反应 (详细)

    Human

    纯化方法

    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    Human IgA1 lambda myeloma protein

    亚型

    IgG1 kappa
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Extracellular and intracellular staining.

    限制

    仅限研究用
  • 溶解方式

    No reconstitution is necessary.

    缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.
    Avoid prolonged exposure to light.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Tierens, Holte, Warsame, Ikonomou, Wang, Chan, Delabie: "Low levels of monoclonal small B cells in the bone marrow of patients with diffuse large B-cell lymphoma of activated B-cell type but not of germinal center B-cell type." in: Haematologica, Vol. 95, Issue 8, pp. 1334-41, (2010) (PubMed).

    Bahler, Pindzola, Swerdlow: "Splenic marginal zone lymphomas appear to originate from different B cell types." in: The American journal of pathology, Vol. 161, Issue 1, pp. 81-8, (2002) (PubMed).

    Kubagawa, Gathings, Levitt, Kearney, Cooper: "Immunoglobulin isotype expression of normal pre-B cells as determined by immunofluorescence." in: Journal of clinical immunology, Vol. 2, Issue 4, pp. 264-9, (1983) (PubMed).

  • 抗原

    Lambda-IgLC (lambda Light Chain (Lambda-IgLC))

    别名

    Ig Lambda Light Chain

    背景

    Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda, both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.,Immunoglobulin lambda, Igl

    分子量

    22.5 kDa
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