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CD36 抗体 (APC)

CD36 适用: 人 FACS 宿主: 小鼠 Monoclonal CB38 APC
产品编号 ABIN1302645
发货至: 中国
  • 抗原 See all CD36 抗体
    CD36
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD36 antibody is conjugated to APC
    应用范围
    • 95
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    Flow Cytometry (FACS)
    特异性
    The mouse monoclonal antibody CB38 (NL07) recognizes an extracellular epitope of CD36 (GPIIIb), a 85-113 kDa integral membrane glycoprotein expressed on platelets, macrophages, endothelial cells, early erythroid cells and megakaryocytes.
    交叉反应 (详细)
    Human
    纯化方法
    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    living human myeloid cells
    克隆位点
    CB38
    亚型
    IgM kappa
    Top Product
    Discover our top product CD36 Primary Antibody
  • 应用备注
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    说明

    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    限制
    仅限研究用
  • 溶解方式
    No reconstitution is necessary.
    缓冲液
    Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    Avoid prolonged exposure to light.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Moniuszko, Kowal, Rusak, Pietruczuk, Dabrowska, Bodzenta-Lukaszyk: "Monocyte CD163 and CD36 expression in human whole blood and isolated mononuclear cell samples: influence of different anticoagulants." in: Clinical and vaccine immunology : CVI, Vol. 13, Issue 6, pp. 704-7, (2006) (PubMed).

    McKenna, Washington, Aquino, Picker, Kroft: "Immunophenotypic analysis of hematogones (B-lymphocyte precursors) in 662 consecutive bone marrow specimens by 4-color flow cytometry." in: Blood, Vol. 98, Issue 8, pp. 2498-507, (2001) (PubMed).

    Kapinsky, Torzewski, Büchler, Duong, Rothe, Schmitz: "Enzymatically degraded LDL preferentially binds to CD14(high) CD16(+) monocytes and induces foam cell formation mediated only in part by the class B scavenger-receptor CD36." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 21, Issue 6, pp. 1004-10, (2001) (PubMed).

    Hoffmann, deCathelineau, Ogden, Leverrier, Bratton, Daleke, Ridley, Fadok, Henson: "Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells." in: The Journal of cell biology, Vol. 155, Issue 4, pp. 649-59, (2001) (PubMed).

    Matasić, Dietz, Vuk-Pavlović: "Dexamethasone inhibits dendritic cell maturation by redirecting differentiation of a subset of cells." in: Journal of leukocyte biology, Vol. 66, Issue 6, pp. 909-14, (2000) (PubMed).

    Fadok, Warner, Bratton, Henson: "CD36 is required for phagocytosis of apoptotic cells by human macrophages that use either a phosphatidylserine receptor or the vitronectin receptor (alpha v beta 3)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 11, pp. 6250-7, (1998) (PubMed).

    Alessio, Greco, Primo, Ghigo, Bosia, Tandon, Ockenhouse, Jamieson, Malavasi: "Platelet activation and inhibition of malarial cytoadherence by the anti-CD36 IgM monoclonal antibody NL07." in: Blood, Vol. 82, Issue 12, pp. 3637-47, (1994) (PubMed).

    Alessio, Roggero, Bussolino, Saitta, Malavasi: "Characterization of the murine monoclonal antibody NL07 specific for the human thrombospondin receptor (CD36 molecule)." in: Current studies in hematology and blood transfusion, Issue 58, pp. 182-6, (1992) (PubMed).

    Alessio, Ghigo, Garbarino, Geuna, Malavasi: "Analysis of the human CD36 leucocyte differentiation antigen by means of the monoclonal antibody NL07." in: Cellular immunology, Vol. 137, Issue 2, pp. 487-500, (1991) (PubMed).

  • 抗原
    CD36
    别名
    CD36 (CD36 产品)
    别名
    BDPLT10 antibody, CHDS7 antibody, FAT antibody, GP3B antibody, GP4 antibody, GPIV antibody, PASIV antibody, SCARB3 antibody, Fat antibody, Scarb3 antibody, GPIIIB antibody, PAS-4 antibody, zgc:92513 antibody, CD36 molecule antibody, CD36 molecule (thrombospondin receptor) antibody, CD36 antibody, Cd36 antibody, cd36 antibody
    背景
    CD36 Molecule,CD36 (fatty acid translocase, FAT) is an 88 kDa ditopic glycosylated protein that belongs to the class B family of scavenger receptors. CD36 is expressed by most resting marginal zone B cells but not by follicular and B1 B cells, and it is rapidly induced on follicular B cells in vitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells, but modulates both primary and secondary antibody response. Similarly to glucose transporter GLUT4, CD36 is translocated from intracellular pools to the plasma membrane following cell stimulation by insulin. In mouse, CD36 is responsible for gustatory perception of long-chain fatty acids.,GPIIIb, GPIV, PAS-4, FAT, Thrombospondin receptor, PASIV
    基因ID
    948
    UniProt
    P16671
    途径
    TLR signaling, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteins
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