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GPX4 抗体 (C-Term)

GPX4 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN129715
发货至: 中国
  • 抗原 See all GPX4 抗体
    GPX4 (Glutathione Peroxidase 4 (GPX4))
    抗原表位
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    C-Term
    适用
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    小鼠
    宿主
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    克隆类型
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    多克隆
    标记
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    This GPX4 antibody is un-conjugated
    应用范围
    • 34
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    Western Blotting (WB), ELISA
    交叉反应
    大鼠, 豚鼠
    产品特性
    Concentration Definition: by UV absorbance at 280 nm
    免疫原
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the of mouse GPx4 protein.
    亚型
    IgG
    Top Product
    Discover our top product GPX4 Primary Antibody
  • 应用备注
    This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 19 kDa in size corresponding to GPx4 protein by western blotting in the appropriate cell lysate or extract.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.15 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    GPX4 (Glutathione Peroxidase 4 (GPX4))
    Abstract
    GPX4 产品
    别名
    GPx-4 antibody, GSHPx-4 antibody, MCSP antibody, PHGPx antibody, snGPx antibody, snPHGPx antibody, Phgpx antibody, gpx-4 antibody, snGpx antibody, cb563 antibody, cb691 antibody, PHGPxa antibody, sb:cb563 antibody, zgc:92253 antibody, wu:fb82e03 antibody, 1700027O09Rik antibody, mtPHGPx antibody, ATGPX4 antibody, F11L15.5 antibody, glutathione peroxidase 4 antibody, GP-GPx4 antibody, glutathione peroxidase 4 antibody, glutathione peroxidase 4a antibody, GPX4 antibody, Gpx4 antibody, gpx4a antibody
    背景
    This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Glutathione Peroxidase 4 (GPx4, also known as PHGPx) functions as an antioxidant and also plays a role in redox regulation, sexual maturation, inflammation, apoptosis, and differentiation.  GPx4 was found to have an important role in preventing lipid peroxidation, and has been discussed primarily as the glutathione peroxidase protecting biomembranes against oxidative stress.  GPx4 can react with free hydrogen peroxide as well as with a wide range of lipid hydroperoxides, including those derived from cholesterol and cholesteryl esters.  GPx4 is the only GPx to use phospholipid hydroperoxides as substrates.  It can also reduce thymine hydroperoxide. In contrast to GPx1 and GPx3, GPx4 can use a wide range of reducing substrates in addition to glutathione.  GPx4 is expressed in high levels in testes, suggesting a role in male fertility.  It has also been identified as an enzymatically inactive structural protein of the mitochondrial capsule of sperm.
    Synonyms: GPX4 antibody, MCSP antibody, PHGPx antibody, Phospholipid hydroperoxidase antibody, Phospholipid hydroperoxide glutathione peroxidase antibody
    基因ID
    625249, 13508533
    UniProt
    O70325
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