FANCE 抗体 (AA 1-13)
Quick Overview for FANCE 抗体 (AA 1-13) (ABIN129609)
抗原
See all FANCE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-13
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Supplier Product No.
- 600-401-673
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Supplier
- Rockland
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原理
- FANCE Antibody
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产品特性
- Synonyms: rabbit anti-FANCE antibody, FANC-E, FANC E, FACE antibody, FAE antibody, Fanconi anemia group E protein, Fanconi anemia complementation group E antibody
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纯化方法
- This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.
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过滤
- Sterile filtered
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免疫原
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Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 1-13 of Human FANCE. This Fanconi anemia protein promotes the nuclear accumulation of FANCC. FANCE protein is part of the FA nuclear complex, binding FANCC & FANCD2. It is required for the nuclear accumulation of FANCC and provides a bridge between the FA complex and FANCD2. FANCC mutants do not bind FANCE or prevent chromosome breakage. LocusLink ID 2178, SwissProt accession number Q9HB96
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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anti-Fanconi Anemia, Complementation Group E (FANCE) (AA 205-482) antibody
FANCE 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group E (FANCE) (AA 1-536) antibodyFANCE 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group E (FANCE) (AA 180-229) antibodyFANCE 适用: 人, Cow, 马, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group E (FANCE) (AA 1-13), (Middle Region) antibodyFANCE 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Application Note: This affinity purified antibody has been tested for use in ELISA against the immunizing peptide. Reactivity in other immunoassays is unknown.
Western Blot Dilution: 1:500- 1:2,000
ELISA Dilution: 1:10,000 - 1:50,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- FANCE (Fanconi Anemia, Complementation Group E (FANCE))
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别名
- FANCE
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背景
- Background: Fanconi anemia group E protein (FANCE) is part of the Fanconi anemia (FA) complex functions in DNA cross-links repair. It is required for the nuclear accumulation of FANCC and provides a critical bridge between the FA complex and FANCD2.
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基因ID
- 2178
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NCBI登录号
- NP_068741
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UniProt
- Q9HB96
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途径
- DNA Damage Repair
抗原
-
