FANCC 抗体 (AA 80-115)
Quick Overview for FANCC 抗体 (AA 80-115) (ABIN129608)
抗原
See all FANCC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-115
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Supplier Product No.
- 600-401-672
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Supplier
- Rockland
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原理
- FANCC Antibody
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交叉反应 （详细）
- This affinity-purified antibody is directed against human FANCC protein.
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产品特性
- Synonyms: rabbit anti-FANCC antibody, FANC-C, FANC C, FAC antibody, FACC antibody, Fanconi anemia group C protein, Fanconi anemia complementation group C antibody
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纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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过滤
- Sterile filtered
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免疫原
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Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 80-115 of Human FANCC.
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 319-558) antibody
FANCC 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 1-558) antibodyFANCC 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (Center) antibodyFANCC 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 1-210) antibodyFANCC 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 1-100) antibodyFANCC 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6E7 unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (C-Term) antibodyFANCC 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 527-555), (C-Term) antibodyFANCC 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB24076 unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 529-558), (C-Term) antibodyFANCC 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (N-Term) antibodyFANCC 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 1-558) antibodyFANCC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Application Note: This affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 63 kDa in size corresponding to FANCC by western blotting in the appropriate human tissue.
Western Blot Dilution: 1:1,000 - 1:3,000
ELISA Dilution: 1:20,000 - 1:80,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.45 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- FANCC (Fanconi Anemia, Complementation Group C (FANCC))
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别名
- FANCC
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背景
- Background: FANCC (also called Protein FACC or Fanconi Anemia Group C protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCC may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. FANCC belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. FANCC is mainly found within the nucleus although some protein is localized in the cytoplasm. This protein is ubiquitously expressed. Defects in FANCC are a cause of Fanconi anemia (FA). FA is a genetically heterogeneous, autosomal recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C.
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基因ID
- 2176, 56118236
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UniProt
- Q00597
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途径
- DNA Damage Repair
抗原
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