FANCG 抗体 (AA 1-25)
Quick Overview for FANCG 抗体 (AA 1-25) (ABIN129607)
抗原
See all FANCG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-25
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Supplier Product No.
- 600-401-671
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Supplier
- Rockland
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原理
- FANCG Antibody
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交叉反应 （详细）
- This affinity-purified antibody is directed against human FANCG protein.
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产品特性
- Synonyms: rabbit anti-FANCG antibody, FANC-G, FANC G, Fanconi anemia group G protein, DNA repair protein XRCC9 antibody, Fanconi anaemia complementation group G antibody, Protein FACG antibody
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纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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过滤
- Sterile filtered
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免疫原
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Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a N-terminal region near amino acids 1-25 of human FANCG protein.
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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anti-Fanconi Anemia Complementation Group G (FANCG) (AA 1-622) antibody
FANCG 适用: 人 WB, ELISA, IF, IP, RNAi 宿主: 小鼠 Monoclonal 2C8 unconjugated
anti-Fanconi Anemia Complementation Group G (FANCG) (C-Term) antibodyVerified FANCG 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Fanconi Anemia Complementation Group G (FANCG) (AA 1-622) antibodyFANCG 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Complementation Group G (FANCG) (Center) antibodyFANCG 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Complementation Group G (FANCG) (AA 343-622) antibodyFANCG 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Complementation Group G (FANCG) (AA 1-622) antibodyFANCG 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Fanconi Anemia Complementation Group G (FANCG) (pSer383) antibodyFANCG 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Complementation Group G (FANCG) (AA 539-568), (C-Term) antibodyFANCG 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Complementation Group G (FANCG) (AA 540-568), (C-Term) antibodyFANCG 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry Dilution: 1:500 - 1:2,000
Application Note: This affinity purified antibody has been tested for use in ELISA, immunohistochemistry and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 69 kDa in size corresponding to FANCG by western blotting in the appropriate human tissue.
Western Blot Dilution: 1:500 - 1:2,000
ELISA Dilution: 1:10,000 - 1:50,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.93 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- FANCG (Fanconi Anemia Complementation Group G (FANCG))
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别名
- FANCG
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背景
- Background: FANCG (also called Protein FACG or DNA-repair protein XRCC9) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCG may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. This protein may also function as a tumor suppressor gene. FANCG belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. FANCG is mainly found within the nucleus although some protein is localized in the cytoplasm. This protein is highly expressed in testis and thymus and is also found in lymphoblasts. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G.
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基因ID
- 2189, 4759336
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UniProt
- O15287
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途径
- DNA Damage Repair
抗原
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