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ATG7 抗体 (AA 550-575)

Name: ATG7 抗体 (AA 550-575)
SKU: ABIN129600
Availability: OutOfStock

This anti-ATG7 antibody is a 兔多克隆 antibody detecting ATG7 in WB, ELISA 和 FM. Suitable for 人. This Primary Antibody has been cited in 7+ publications.

(7 references)

产品编号 ABIN129600

Supplier Product No.: 600-401-487

发货至: 中国

Quick Overview for ATG7 抗体 (AA 550-575) (ABIN129600)

抗原

See all ATG7 抗体

ATG7 (ATG7 Autophagy Related 7 (ATG7))

适用

人

宿主

兔

克隆类型

多克隆

标记

This ATG7 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Fluorescence Microscopy (FM)

Discover our top product ATG7 Primary Antibody

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AA 550-575

Supplier Product No.

600-401-487

Supplier

Rockland

原理

APG7 Antibody

交叉反应（详细）

Reactivity occurs against human Apg7 protein.

产品特性

Synonyms: rabbit anti-APG7 Antibody, APG-7, APG 7, APG7 autophagy 7-like antibody, APG7 like antibody, APG7L antibody, ATG 7 antibody, ATG-7 antibody, ATG7 autophagy related 7 homolog antibody

纯化方法

This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.

过滤

Sterile filtered

免疫原

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 550-575 of Human Apg7 protein.
Immunogen Type: Conjugated Peptide

亚型

IgG
anti-ATG7 Autophagy Related 7 (ATG7) (AA 500-676) antibody
ATG7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 477-698) antibody
ATG7 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 540-569), (C-Term) antibody
ATG7 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7474 unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 22-51) antibody
ATG7 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 494-523) antibody
ATG7 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) antibody
ATG7 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (AA 558-703) antibody
ATG7 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7D3E5 unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody
ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (HRP)
ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal HRP

anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (FITC)
ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal FITC

应用备注

Application Note: This affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 78 kDa in size corresponding to human Apg7 by western blotting in the appropriate cell lysate or extract. Human Apg7 has been reported to form a homodimer at approximately 160 kDa.
Western Blot Dilution: 1:500 - 1:2,000
ELISA Dilution: 1:300,000 - 1:400,000
IF Microscopy Dilution: User Optimized
Other: User Optimized

限制

仅限研究用
状态

Liquid

浓度

1.46 mg/mL

缓冲液

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

有效期

12 months
Bhattacharya, Parillon, Zeng, Han, Eissa: "Deficiency of autophagy in dendritic cells protects against experimental autoimmune encephalomyelitis." in: The Journal of biological chemistry, Vol. 289, Issue 38, pp. 26525-32, (2015) (PubMed).

Abdel Fattah, Bhattacharya, Herron, Safdar, Eissa: "Critical role for IL-18 in spontaneous lung inflammation caused by autophagy deficiency." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 11, pp. 5407-16, (2015) (PubMed).

Fung, Chen, Grandis, Duvvuri: "EGFR tyrosine kinase inhibition induces autophagy in cancer cells." in: Cancer biology & therapy, Vol. 13, Issue 14, pp. 1417-24, (2013) (PubMed).

Shin, Fattah, Bhattacharya, Ko, Eissa: "Inflammasome activation by altered proteostasis." in: The Journal of biological chemistry, Vol. 288, Issue 50, pp. 35886-95, (2013) (PubMed).

Liu, Ko, Xu, Fattah, Xiang, Jagannath, Ishii, Komatsu, Eissa: "Transient aggregation of ubiquitinated proteins is a cytosolic unfolded protein response to inflammation and endoplasmic reticulum stress." in: The Journal of biological chemistry, Vol. 287, Issue 23, pp. 19687-98, (2012) (PubMed).

Sarkar, Perlstein, Imarisio, Pineau, Cordenier, Maglathlin, Webster, Lewis, OKane, Schreiber, Rubinsztein: "Small molecules enhance autophagy and reduce toxicity in Huntington's disease models." in: Nature chemical biology, Vol. 3, Issue 6, pp. 331-8, (2007) (PubMed).

Sarkar, Davies, Huang, Tunnacliffe, Rubinsztein: "Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein." in: The Journal of biological chemistry, Vol. 282, Issue 8, pp. 5641-52, (2007) (PubMed).
抗原

ATG7 (ATG7 Autophagy Related 7 (ATG7))

别名

ATG7

背景

Background: Apg7 is the human gene product similar in homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae Apg7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes.

基因ID

10533

NCBI登录号

NP_001129503

UniProt

O95352

途径

Response to Water Deprivation, Autophagy