IBTK 抗体 (Internal Region)
Quick Overview for IBTK 抗体 (Internal Region) (ABIN129599)
抗原
See all IBTK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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Supplier Product No.
- 600-401-486
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Supplier
- Rockland
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原理
- BTB1 Antibody
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产品特性
- Synonyms: rabbit anti-BTB1 Antibody, BTB-1, BTB 1, IBTK, BTKI, Inhibitor of Bruton tyrosine kinase, BTK Binding Protein antibody
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纯化方法
- This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.
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过滤
- Sterile filtered
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免疫原
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Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of Human Btb1. Btb1 is a currently uncharacterized human ankyrin repeat protein BAA92655. This protein has been suggested to bind to CUL3.
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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anti-Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK) (AA 586-613) antibody
IBTK 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24652 unconjugated
anti-Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK) (AA 589-617), (Middle Region) antibodyIBTK 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK) (AA 1-1353) antibodyIBTK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK) (C-Term) antibodyIBTK 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK) (AA 900-1200) antibodyIBTK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Application Note: This affinity purified antibody has been tested for use in ELISA against the immunizing peptide. Reactivity in other immunoassays is unknown.
Western Blot Dilution: 1:500 - 1:3,000
ELISA Dilution: 1:5,000 - 1:25,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.63 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))
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别名
- IBTK
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背景
- Background: BTB1 acts as an inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development. It down-regulates BTK kinase activity, leading to interference with BTK-mediated calcium mobilization and NF-kappa-B-driven transcription.
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基因ID
- 25998
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NCBI登录号
- NP_001287835
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UniProt
- Q9P2D0
抗原
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