USP18 抗体 (AA 25-50)
Quick Overview for USP18 抗体 (AA 25-50) (ABIN129593)
抗原
See all USP18 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-50
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Supplier Product No.
- 600-401-476
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Supplier
- Rockland
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原理
- UBP43 Antibody
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交叉反应 （详细）
- This affinity-purified antibody is directed against human UBP43 protein.
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产品特性
- Synonyms: rabbit anti-UBP43 antibody, rabbit anti-USP18 antibody, rabbit anti-ISG43 antibody, 43 kDa ISG15 specific protease antibody, hUBP43 antibody, Interferon Stimulated Gene 43 kD antibody, ISG15 Specific Processing Protease antibody, ISG43 antibody, Ubiquitin Specific Peptidase 18 antibody, Ubl carboxyl-terminal hydrolase 18, Ubl thioesterase 18
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纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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过滤
- Sterile filtered
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免疫原
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Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 25-50 of human UBP43 protein.
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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anti-Ubiquitin Specific Peptidase 18 (USP18) (AA 200-300) antibody
USP18 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 18 (USP18) (AA 18-118), (C-Term) antibodyUSP18 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 18 (USP18) antibodyUSP18 适用: 人, 小鼠, 大鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 18 (USP18) (AA 1-372) antibodyUSP18 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 18 (USP18) (AA 1-372) antibodyUSP18 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 18 (USP18) (AA 1-372) antibodyUSP18 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 18 (USP18) (N-Term) antibodyUSP18 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 18 (USP18) (AA 110-159) antibodyUSP18 适用: 人, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 18 (USP18) (N-Term) antibodyUSP18 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 18 (USP18) (N-Term) antibodyUSP18 适用: 人, 小鼠, 大鼠, 马, Cow, 犬, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Application Note: This affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 43 kDa in size corresponding to UBP43 by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:500 - 1:2,000
ELISA Dilution: 1:10,000 - 1:50,000
IF Microscopy Dilution: User Optimized
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.9 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- USP18 (Ubiquitin Specific Peptidase 18 (USP18))
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别名
- USP18
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背景
- Background: UBP43 (also known as ISG43, Ubl thiolesterase 18, ISG15-specific processing protease, 43 kDa ISG15-specific protease, ubiquitin specific protease 18 or USP18) is a member of the deubiquitinating protease family of enzymes, which removes ubiquitin adducts from a broad range of protein substrates. Deletion of the UBP43 gene in mouse leads to a massive increase of ISG15 conjugates in tissues indicating that UBP43 is a major ISG15-specific protease. UBP43 is the first ISG15-specific protease reported. Both ISG15 and UBP43 genes are known to be strongly induced by interferon, genotoxic stress, and viral infection. Thus UBP43 may be necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms.
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基因ID
- 11274, 32313610
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UniProt
- Q9UMW8
抗原
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