MMP12 抗体
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北京 101111
Quick Overview for MMP12 抗体 (ABIN127325)
抗原
See all MMP12 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody recognizes the MMP-12.
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纯化方法
- Affinity Chromatography.
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免疫原
- Synthetic peptide surrounding amino acid 460 of Human MMP-12
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应用备注
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Western Blot: 0.5-4.0 μg/mL. Mouse small intestine tissue lysate can be used as a Positive Control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 30 % Glycerol and 0.02 % Thimerosal.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
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别名
- MMP-12
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背景
- The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-12 may contribute to elastin degradation occurring in granulomatous skin diseases and may also participate in macrophage migration through the epidermal and vascular basement membranes in inflammatory disorders.Synonyms: HME, ME, MMP12, Macrophage elastase, Macrophage metalloelastase, Matrix metalloproteinase-12
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基因ID
- 4321
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NCBI登录号
- NP_002417
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UniProt
- P39900
抗原
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