NOXA 抗体
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北京 101111
Quick Overview for NOXA 抗体 (ABIN127296)
抗原
See all NOXA (PMAIP1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody recognizes mainly ~16 kDa band. A ~34 kDa band is also detected to the lesser extent.
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纯化方法
- Protein A chromatography
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免疫原
- Synthetic peptide surrounding amino acid 100 of human Noxa
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anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (AA 1-54) antibody
PMAIP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (AA 1-54) antibodyPMAIP1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1A2D3 unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (AA 1-136) antibodyPMAIP1 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) antibodyPMAIP1 适用: 人 WB, IF, IHC, FACS 宿主: 小鼠 Monoclonal 114C307-1 unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (AA 1-136) antibodyPMAIP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (Internal Region) antibodyVerified PMAIP1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (N-Term) antibodyPMAIP1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 0.5-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- BPS containing 0.5 % BSA, 30 % glycerol, and 0.01 % thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at -20 °C to -70 °C.
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- NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
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别名
- NOXA
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背景
- Noxa is a BH3-only member of the Bcl-2 family. Expression of Noxa gene involves direct activation of its promotor by p53. Increased expression of Noxa protein occurs in normal thymocytes but not in p53-deficient thymocytes. Coimmunoprecipitation data suggest that Noxa protein may interact with proteins belonging to the Bcl-2 family, such as Bcl-xL and Mcl-1. Blocking the endogenous Noxa induction results in the suppression of apoptosis. These suggest Noxa may represent a candidate mediator of p53-induced apoptosis.Synonyms: PMA-induced protein 1, PMAIP1, Phorbol-12-myristate-13-acetate-induced protein 1
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基因ID
- 5366
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NCBI登录号
- NP_066950
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UniProt
- Q13794
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途径
- p53 Pathway, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
抗原
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