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HDAC6 抗体 (N-Term)

HDAC6 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN127242
发货至: 中国
  • 抗原 See all HDAC6 抗体
    HDAC6 (Histone Deacetylase 6 (HDAC6))
    抗原表位
    • 26
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    N-Term
    适用
    • 122
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    人, 小鼠, 大鼠
    宿主
    • 109
    • 16
    • 1
    克隆类型
    • 102
    • 24
    多克隆
    标记
    • 71
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    This HDAC6 antibody is un-conjugated
    应用范围
    • 101
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    • 15
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    • 9
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The antibody detects ~134 kDa HDAC-6. This antibody does not cross-react with other HDAC proteins including HDAC1, 2, 3, 4, 5, 7, and 8.
    纯化方法
    Affinity Chromatography.
    免疫原
    Synthetic peptide mapping to the N-terminus of mouse HDAC-6.
    Top Product
    Discover our top product HDAC6 Primary Antibody
  • 应用备注
    Western Blot: 0.5-4 μg/mL. Immunohistochemistry: 20 μg/mL. Positive Control: Mouse small intestine tissue lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    PBS, pH 7.2, containing 30 % Glycerol, 0.5 % BSA and 0.01 % thimerosal.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or (in aliquots) at -70 °C for longer.
  • 抗原
    HDAC6 (Histone Deacetylase 6 (HDAC6))
    别名
    HDAC6 (HDAC6 产品)
    别名
    HD6 antibody, Hd6 antibody, Hdac5 antibody, Sfc6 antibody, mHDA2 antibody, CG6170 antibody, DHDAC2 antibody, DmHDAC2 antibody, Dmel\\CG6170 antibody, HDAC antibody, HDAC2 antibody, dHDAC2 antibody, dHDAC6 antibody, dmHDA404 antibody, hdac6 antibody, MGC53140 antibody, wu:fc31d02 antibody, dsim_GLEANR_17355 antibody, DsimGD17207 antibody, GD17207 antibody, HDAC6 antibody, ATHDA6 antibody, AXE1 antibody, HISTONE DEACETYLASE 6 antibody, MDC12.7 antibody, MDC12_7 antibody, RNA-MEDIATED TRANSCRIPTIONAL SILENCING 1 antibody, RPD3B antibody, RTS1 antibody, SIL1 antibody, histone deacetylase 6 antibody, histone deacetylase 6 antibody, Histone deacetylase 6 antibody, histone deacetylase 6 L homeolog antibody, GD17207 gene product from transcript GD17207-RB antibody, Histone DeAcetylase antibody, HDAC6 antibody, Hdac6 antibody, hdac6.L antibody, hdac6 antibody, Dsim\HDAC6 antibody, PTRG_03035 antibody, HDA6 antibody, hda-6 antibody
    背景
    Human HDAC6 (1215 a.a. residues) possesses two separate putative catalytic domains, both of which are fully functional and contribute independently to the overall activity of HDAC6. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. HDAC6 may participate in coordinating expression of a group of genes involved in the remoldeling of chromatin during cell differentiation.Synonyms: HD6, Histone deacetylase 6, JM21, KIAA0901
    基因ID
    10013
    NCBI登录号
    NP_006035
    UniProt
    Q9UBN7
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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