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HDAC1 抗体 (C-Term)

This anti-HDAC1 antibody is a 兔 多克隆 antibody detecting HDAC1 in WB, IP 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN127232
发货至: 中国

Quick Overview for HDAC1 抗体 (C-Term) (ABIN127232)

抗原

See all HDAC1 抗体
HDAC1 (Histone Deacetylase 1 (HDAC1))

适用

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人, 小鼠, 大鼠

宿主

  • 124
  • 26
  • 2

克隆类型

  • 120
  • 32
多克隆

标记

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This HDAC1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    • 1
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    C-Term

    特异性

    The antibody detects the 62 kDa histone deacetylase 1. It does not cross-react with other HDAC proteins including HDAC2, 3, 4, 5, 6, 7, and 8.

    纯化方法

    Affinity Purified

    免疫原

    Synthetic peptide corresponding to the C-terminus of human HDAC1
  • 应用备注

    Western blotting (0.5-4 μg/mL). Immunoprecipitation (10-20 μg/mL). Immunohistochemistry (10-20 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid Repeated freeze/defrost cycles.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. For long-term storage, aliquot and freeze at -70 °C.
  • 抗原

    HDAC1 (Histone Deacetylase 1 (HDAC1))

    别名

    HDAC1

    背景

    HDAC1 is an active component of transcriptional corepressor complexes which can be recruited to specific promoter regions via transcriptional factors. HDAC1 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, which leads to the inhibition of gene transcription.Synonyms: HD1, Histone deacetylase 1, RPD3L1

    基因ID

    3065

    NCBI登录号

    NP_004955

    UniProt

    Q13547

    途径

    Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis
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