HDAC1 抗体 (C-Term)
Quick Overview for HDAC1 抗体 (C-Term) (ABIN127232)
抗原
See all HDAC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- The antibody detects the 62 kDa histone deacetylase 1. It does not cross-react with other HDAC proteins including HDAC2, 3, 4, 5, 6, 7, and 8.
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纯化方法
- Affinity Purified
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免疫原
- Synthetic peptide corresponding to the C-terminus of human HDAC1
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应用备注
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Western blotting (0.5-4 μg/mL). Immunoprecipitation (10-20 μg/mL). Immunohistochemistry (10-20 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid Repeated freeze/defrost cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. For long-term storage, aliquot and freeze at -70 °C.
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- HDAC1 (Histone Deacetylase 1 (HDAC1))
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别名
- HDAC1
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背景
- HDAC1 is an active component of transcriptional corepressor complexes which can be recruited to specific promoter regions via transcriptional factors. HDAC1 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, which leads to the inhibition of gene transcription.Synonyms: HD1, Histone deacetylase 1, RPD3L1
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基因ID
- 3065
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NCBI登录号
- NP_004955
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UniProt
- Q13547
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途径
- Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis
抗原
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