KISS1 抗体 (N-Term)
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Quick Overview for KISS1 抗体 (N-Term) (ABIN127218)
抗原
See all KISS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- The antibody recognizes 16 kDa human KiSS-1.
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纯化方法
- Affinity Chromatography.
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免疫原
- Synthetic peptide near the N-terminus of Mouse KiSS-1.
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应用备注
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Western Blot: 0.5-4.0 μg/mL. Jurkat cell lysate can be used as a Positive Control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, pH 7.2 containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
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别名
- KiSS-1
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背景
- KiSS-1 has been reported to suppress metastases of melanomas and breast carcinomas without affecting tumorigenicity. Human KiSS-1 transcripts are predominately expressed in the brain and placenta. Expression of KiSS-1 reduces the level of NFκB p50/p65 binding to the MMP9 promoter and correlates with diminished expression of the 92 kDa type IV collagenase (MMP-9). KiSS-1 may regulate events downstream of cell-matrix adhesion in mechanisms involving cytoskeletal reorganization.Synonyms: KISS1, Metastasis-suppressor KiSS-1, PP5098
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基因ID
- 3814
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NCBI登录号
- NP_002247
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UniProt
- Q15726
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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