Western Blot: 0.5-4.0 μg/mL. Jurkat cell lysate can be used as a Positive Control. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
-20 °C/-80 °C
储存方法
Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
抗原
KISS1
(KiSS-1 Metastasis-Suppressor (KISS1))
别名
KiSS-1
背景
KiSS-1 has been reported to suppress metastases of melanomas and breast carcinomas without affecting tumorigenicity. Human KiSS-1 transcripts are predominately expressed in the brain and placenta. Expression of KiSS-1 reduces the level of NFκB p50/p65 binding to the MMP9 promoter and correlates with diminished expression of the 92 kDa type IV collagenase (MMP-9). KiSS-1 may regulate events downstream of cell-matrix adhesion in mechanisms involving cytoskeletal reorganization.Synonyms: KISS1, Metastasis-suppressor KiSS-1, PP5098