PKC beta 抗体 (C-Term)
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Quick Overview for PKC beta 抗体 (C-Term) (ABIN127129)
抗原
See all PKC beta (PRKCB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- The antibody recognizes 60-75 kDa PKC beta isoforms from samples of human, mouse, rat, pig and bovine origins. A 40 kDa band can also be detected, presumably to be a shorter form of PKC isoforms.
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纯化方法
- Protein A purified
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免疫原
- Synthetic peptide corresponding to the C-terminus of human PKC.
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应用备注
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Western Blot: 1-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- PKC beta (PRKCB) (Protein Kinase C, beta (PRKCB))
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别名
- PRKCB
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背景
- PKC (Protein kinase C) is a calcium-dependent and phospholipid-dependent enzyme that is activated in vivo by the lipid diacylglycerol. PKC has been shown to be involved in signal transduction and various aspects of neoplastic transformation. PKC contains an amino terminal regulatory domain and a carboxy terminal catalytic domain joined by a hinge region. Cleavage of protein kinase C in vitro results in the generation of two functional fragments corresponding to these two domains.Synonyms: PKC beta, PKC-B, PKC-beta, PKCB, PRKCB1, Protein kinase C beta type
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基因ID
- 5579
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NCBI登录号
- NP_002729
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UniProt
- P05771
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途径
- WNT signaling, TCR Signaling, Thyroid Hormone Synthesis, Nuclear Hormone Receptor Binding, Chromatin Binding, Myometrial Relaxation and Contraction, VEGF Signaling, Unfolded Protein Response, BCR Signaling
抗原
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