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TLR1 抗体

This anti-TLR1 antibody is a 山羊 多克隆 antibody detecting TLR1 in WB 和 EIA. Suitable for 人.
产品编号 ABIN127125
发货至: 中国

Quick Overview for TLR1 抗体 (ABIN127125)

抗原

See all TLR1 抗体
TLR1 (Toll-Like Receptor 1 (TLR1))

适用

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宿主

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山羊

克隆类型

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多克隆

标记

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This TLR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 纯化方法

    Antigen affinity chromatography

    免疫原

    Recombinant human TLR1
  • 应用备注

    Western Blot: 1: 200 - 1: 1000. ELISA: 1: 100 - 1: 500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody undiluted (in aliquots) at -20 °C to -70 °C.
  • 抗原

    TLR1 (Toll-Like Receptor 1 (TLR1))

    别名

    CD281 / TLR1

    背景

    The TLR (toll-like receptors) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1, as well as the other TLR family members, are type I transmembrane receptors that characteristically contain an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFκB and suggests that these receptors are involved in mediating inflammatory responses. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes. TLR6 is highly homologous to TLR1, sharing greater that 65 % sequence identity, and, like other members of TLR family, it induces NFκB signaling upon activation.Synonyms: KIAA0012, TIL, Toll-like receptor 1, Toll/interleukin-1 receptor-like protein

    基因ID

    9606

    UniProt

    Q15399

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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