TLR1 抗体
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北京 101111
Quick Overview for TLR1 抗体 (ABIN127125)
抗原
See all TLR1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antigen affinity chromatography
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免疫原
- Recombinant human TLR1
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应用备注
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Western Blot: 1: 200 - 1: 1000. ELISA: 1: 100 - 1: 500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at -20 °C to -70 °C.
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- TLR1 (Toll-Like Receptor 1 (TLR1))
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别名
- CD281 / TLR1
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背景
- The TLR (toll-like receptors) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1, as well as the other TLR family members, are type I transmembrane receptors that characteristically contain an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFκB and suggests that these receptors are involved in mediating inflammatory responses. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes. TLR6 is highly homologous to TLR1, sharing greater that 65 % sequence identity, and, like other members of TLR family, it induces NFκB signaling upon activation.Synonyms: KIAA0012, TIL, Toll-like receptor 1, Toll/interleukin-1 receptor-like protein
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基因ID
- 9606
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UniProt
- Q15399
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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