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MAP3K11 抗体 (C-Term)

MAP3K11 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN127111
发货至: 中国
  • 抗原 See all MAP3K11 抗体
    MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))
    抗原表位
    • 15
    • 10
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 54
    • 34
    • 28
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 49
    • 4
    克隆类型
    • 50
    • 4
    多克隆
    标记
    • 24
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAP3K11 antibody is un-conjugated
    应用范围
    • 37
    • 24
    • 14
    • 14
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    The antibody recognizes 92 kDa MLK3. It does not cross react with MLK1, MLK2 and other mixed lineage kinases.
    纯化方法
    Affinity purified
    免疫原
    Synthetic peptide mapping to the C-terminus of human MLK3.
    Top Product
    Discover our top product MAP3K11 Primary Antibody
  • 应用备注
    Western Blot: 0.5-4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原
    MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))
    别名
    MAP3K11 (MAP3K11 产品)
    别名
    MEKK11 antibody, MLK-3 antibody, MLK3 antibody, PTK1 antibody, SPRK antibody, 2610017K16Rik antibody, Mlk3 antibody, Mlk-3 antibody, RHOE antibody, mitogen-activated protein kinase kinase kinase 11 antibody, MAP3K11 antibody, Map3k11 antibody
    背景
    MLK3 (Mixed lineage kinase 3) is a serine/threonine kinase that has an amino-terminal SH3 domain followed by the kinase domain and two leucine zippers, a cdc42/Rac1 binding (CRIB) domain and several other domains/motifs at the carboxy-terminal region. MLK3 functions as a MAPKKK of the SAPK/JNK stress pathway by directly phosphorylating SEK1/MKK4 and MKK7, although it is controversial whether MLK3 is involved in p38 stress pathway activation. MLK3 also functions as an IκB kinase and mediates the activation of the transcriptional factor NF-κB stimulated by CD3/CD28, suggesting a role for MLK3 in immune and inflammatory responses.Synonyms: MLK3, Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, PTK1, Src-homology 3 domain-containing proline-rich kinase
    基因ID
    4296
    NCBI登录号
    NP_002410
    UniProt
    Q16584
    途径
    MAPK Pathway, Interferon-gamma Pathway
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