MAP3K11 抗体 (C-Term)
Quick Overview for MAP3K11 抗体 (C-Term) (ABIN127111)
抗原
See all MAP3K11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- The antibody recognizes 92 kDa MLK3. It does not cross react with MLK1, MLK2 and other mixed lineage kinases.
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纯化方法
- Affinity purified
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免疫原
- Synthetic peptide mapping to the C-terminus of human MLK3.
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) (AA 741-847) antibody
MAP3K11 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 3D11 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) (pSer281), (pThr277) antibodyMAP3K11 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) (AA 355-460) antibodyMAP3K11 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) (AA 536-693) antibodyMAP3K11 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) (pSer674) antibodyMAP3K11 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) (AA 741-847) antibodyMAP3K11 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) (AA 719-768) antibodyMAP3K11 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Hamster, 猴, Bat, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) (pSer674) antibodyMAP3K11 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) (AA 140-260) antibodyMAP3K11 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) (Middle Region) antibodyMAP3K11 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 0.5-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))
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别名
- MAP3K11
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背景
- MLK3 (Mixed lineage kinase 3) is a serine/threonine kinase that has an amino-terminal SH3 domain followed by the kinase domain and two leucine zippers, a cdc42/Rac1 binding (CRIB) domain and several other domains/motifs at the carboxy-terminal region. MLK3 functions as a MAPKKK of the SAPK/JNK stress pathway by directly phosphorylating SEK1/MKK4 and MKK7, although it is controversial whether MLK3 is involved in p38 stress pathway activation. MLK3 also functions as an IκB kinase and mediates the activation of the transcriptional factor NF-κB stimulated by CD3/CD28, suggesting a role for MLK3 in immune and inflammatory responses.Synonyms: MLK3, Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, PTK1, Src-homology 3 domain-containing proline-rich kinase
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基因ID
- 4296
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NCBI登录号
- NP_002410
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UniProt
- Q16584
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途径
- MAPK Pathway, Interferon-gamma Pathway
抗原
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