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ILK 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects ILK in WB 和 IHC (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN127105
发货至: 中国
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Quick Overview for ILK 抗体 (C-Term) (ABIN127105)

抗原

See all ILK 抗体
ILK (Integrin-Linked Kinase (ILK))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ILK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    特异性

    The antibody recognizes 51 kDa of ILK1.

    纯化方法

    Antigen affinity chromatography

    免疫原

    Synthetic peptide corresponding to the C-terminus of human ILK-1.
  • 应用备注

    Western Blot: 0.5-4 μg/mL. Immunohistochemistry: 10-20 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原

    ILK (Integrin-Linked Kinase (ILK))

    别名

    Integrin-Linked Protein Kinase

    背景

    ILKs (Integrin-linked kinases) in combination with integrins and growth factors regulate cell survival, cell cycle, cell-cell adhesion and cell motility. ILK functions as a scaffold bridging the extra-cellular matrix (ECM) and growth factor receptors to the actin cytoskeleton through interactions with integrin, PINCH (which links ILK to the RTKs via Nck2), CH-ILKBP and affixin. ILK phosphorylates several cellular targets including Akt, GSK-3, myosin light chain 2, as well as affixin. These phosphorylation events are key regulatory steps in modulating the activities of the targets.Synonyms: 59 kDa serine/threonine-protein kinase, ILK, ILK-1, ILK-2, ILK1, ILK2, p59ILK

    基因ID

    3611

    NCBI登录号

    NP_001014794

    UniProt

    Q13418

    途径

    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
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