Caspase 6 抗体 (C-Term)
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Quick Overview for Caspase 6 抗体 (C-Term) (ABIN127060)
抗原
See all Caspase 6 (CASP6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- The antibody detects a full length (35 kDa) and the cleaved fragment (18 kDa) of Caspase-6.
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纯化方法
- Affinity Purified
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免疫原
- Synthetic peptide mapping to the C-terminus of Rat Caspase-6 large fragment.
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应用备注
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Western Blot: 0.5-4 μg/mL. Jurkat cell lysate, mouse intestine, and rat kidney tissue lysate can be used as a positivecontrols.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, pH 7.2 containing 30 % Glycero, 0.01 Thimerosal, 0.5 % BSA
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
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别名
- Caspase-6
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背景
- Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-6 is one of the major executioner caspases functioning in cellular apoptotic processes. Similar as other caspases, caspase-6 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Together with caspase-3, caspase-6 is one of the major caspases in apoptotic cells, and functions downstream of apoptosis inhibitors Bcl-2 and Bcl-xL. Caspase-6 has also been shown involving in the proteolysis of poly (ADP-ribose) polymerase (PARP) and nuclear lamin A.Synonyms: Apoptotic protease Mch-2, CASP-6, CASP6, MCH-2, MCH2
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基因ID
- 839
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NCBI登录号
- NP_001217
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UniProt
- P55212
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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