Cathepsin B 抗体
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北京 101111
Quick Overview for Cathepsin B 抗体 (ABIN127046)
抗原
See all Cathepsin B (CTSB) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The purified antibody detects both the proform (37-43 kDa) and the mature form (25 kDa) of Cathepsin B.
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse and Rat.
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纯化方法
- Affinity Chromatography.
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免疫原
- Synthetic peptide surrounding amino acid 322 of human cathepsins B
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anti-Cathepsin B (CTSB) (AA 1-339) antibody
CTSB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 251-339) antibodyCTSB 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 82-333) antibodyCTSB 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 42-339) antibodyCTSB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 1-339) antibodyCTSB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cathepsin B (CTSB) antibodyCTSB 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Cathepsin B (CTSB) antibodyKD Validated CTSB 适用: 人 WB 宿主: 兔 Monoclonal 23GB1130 unconjugated Recombinant Antibody
anti-Cathepsin B (CTSB) (AA 129-333) antibodyCTSB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 129-333) antibodyCTSB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 129-333) antibodyCTSB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 0.5-4 μg/mL. Immunohistochemistry: 10-20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, pH 7.2 containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -20 °C to -70 °C.
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- Cathepsin B (CTSB)
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别名
- Cathepsin B
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背景
- Cathepsin B is a normal lysosomal cysteine proteinase that is expressed in all cells. It is synthesized as an inactive 43 kDa pro-enzyme which, by removal of a 62 amino acid propeptide, is activated to the single-chain form of 31 kDa or the two-chain form (25 and 5 kDa subunits). Matured cathepsin B is normally localized in the lysosomes where it functions in protein turnover. Cathepsin B is also shown capable of degrading extracellular matrix proteins. Elevated levels of cathepsin B correlate with malignancy suggesting that this enzyme may be a useful prognostic marker for several types of human cancers.Synonyms: APP secretase, APPS, CPSB, CTSB, Cathepsin B1
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基因ID
- 1508
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NCBI登录号
- NP_001899
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UniProt
- P07858
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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