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Cathepsin B 抗体

CTSB 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN127046
发货至: 中国
  • 抗原 See all Cathepsin B (CTSB) 抗体
    Cathepsin B (CTSB)
    适用
    • 56
    • 26
    • 24
    • 7
    • 1
    人, 小鼠, 大鼠
    宿主
    • 43
    • 12
    • 3
    • 2
    • 1
    克隆类型
    • 46
    • 15
    多克隆
    标记
    • 28
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cathepsin B antibody is un-conjugated
    应用范围
    • 44
    • 23
    • 21
    • 17
    • 14
    • 13
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The purified antibody detects both the proform (37-43 kDa) and the mature form (25 kDa) of Cathepsin B.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse and Rat.
    纯化方法
    Affinity Chromatography.
    免疫原
    Synthetic peptide surrounding amino acid 322 of human cathepsins B
    Top Product
    Discover our top product CTSB Primary Antibody
  • 应用备注
    Western Blot: 0.5-4 μg/mL. Immunohistochemistry: 10-20 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    PBS, pH 7.2 containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -20 °C to -70 °C.
  • 抗原
    Cathepsin B (CTSB)
    别名
    Cathepsin B (CTSB 产品)
    别名
    APPS antibody, CPSB antibody, CB antibody, apps antibody, cpsb antibody, LOC692390 antibody, CTSB antibody, cathepsin B antibody, cathepsin B S homeolog antibody, CTSB antibody, Ctsb antibody, ctsb.S antibody, LOC692390 antibody
    背景
    Cathepsin B is a normal lysosomal cysteine proteinase that is expressed in all cells. It is synthesized as an inactive 43 kDa pro-enzyme which, by removal of a 62 amino acid propeptide, is activated to the single-chain form of 31 kDa or the two-chain form (25 and 5 kDa subunits). Matured cathepsin B is normally localized in the lysosomes where it functions in protein turnover. Cathepsin B is also shown capable of degrading extracellular matrix proteins. Elevated levels of cathepsin B correlate with malignancy suggesting that this enzyme may be a useful prognostic marker for several types of human cancers.Synonyms: APP secretase, APPS, CPSB, CTSB, Cathepsin B1
    基因ID
    1508
    NCBI登录号
    NP_001899
    UniProt
    P07858
    途径
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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