Caspase 7 抗体 (Cleavage Site)
Our Local Distributor
北京 101111
Quick Overview for Caspase 7 抗体 (Cleavage Site) (ABIN127023)
抗原
See all Caspase 7 (CASP7) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Cleavage Site
-
特异性
- The antibody detects the full length (35-37 kDa) and the large fragment (20 kDa) of processed caspase-7 by Western blotting.
-
纯化方法
- Immunoaffinity purified
-
免疫原
- Synthetic peptide corresponding to residues surrounding the cleavage site of human caspase-7 large fragment
-
-
-
-
应用备注
-
Western Blot: 0.5-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 0.2 mg/mL
-
缓冲液
- PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C/-80 °C
-
储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
-
-
- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
-
别名
- Caspase-7
-
背景
- Caspase-7 is a 34 kDa protein consisting of two subunits and a short prodomain. The procaspase-7 can be activated by cleavage by upstream caspases to form active caspase-7 in apoptosis. Once activated, caspase-7 cleaves many of the same substrates as caspase-3, including poly (ADP-ribose) polymerase (PARP) and sterol regulatory element binding proteins (SREBPs).Synonyms: Apoptotic protease Mch-3, CASP-7, CASP7, CMH-1, ICE-like apoptotic protease 3, MCH3
-
基因ID
- 840
-
NCBI登录号
- NP_001218
-
UniProt
- P55210
-
途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
-