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BOK 抗体

BOK 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN126989
发货至: 中国
  • 抗原 See all BOK 抗体
    BOK (BCL2-Related Ovarian Killer (BOK))
    适用
    • 45
    • 12
    • 6
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 43
    • 2
    克隆类型
    • 45
    多克隆
    标记
    • 20
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BOK antibody is un-conjugated
    应用范围
    • 28
    • 28
    • 13
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts to Bok.
    纯化方法
    Affinity purified
    免疫原
    Synthetic peptide surrounding amino acid 44 of rat BOK.
    Top Product
    Discover our top product BOK Primary Antibody
  • 应用备注
    Western Blot: 0.5-4g/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原
    BOK (BCL2-Related Ovarian Killer (BOK))
    别名
    BOK / BCL2L9 (BOK 产品)
    别名
    BOK antibody, bok antibody, zgc:100979 antibody, zgc:64041 antibody, BCL2L9 antibody, BOKL antibody, Bok-BH3 antibody, AI847676 antibody, AU021146 antibody, matador antibody, mtd antibody, BOK, BCL2 family apoptosis regulator antibody, BCL2-related ovarian killer a antibody, BCL2-related ovarian killer b antibody, BCL2-related ovarian killer antibody, BOK antibody, boka antibody, bokb antibody, Bok antibody
    背景
    Bok (Bcl-2-related ovarian killer) is a pro-apoptotic Bcl-2 family protein identified in the ovary based on its dimerization with the anti-apoptotic protein Mcl-1. In addition to the Bcl-2 homology (BH) domains 1 and 2 and the transmembrane sequence, Bok also has a BH3 domain believed to be important for dimerization with selective anti-apoptotic Bcl-2 proteins and cell killing. Bok interacts strongly with some (Mcl-1, BHRF1, and Bfl-1) but not other (Bcl-2, Bcl-xL, and Bcl-w) anti-apoptotic members. In addition, cell killing induced by Bok was suppressed following coexpression with Mcl-1 and BHRF1, but not with Bcl-2, further indicating that Bok heterodimerized only with selective anti-apoptotic Bcl-2 proteins. Bok was highly expressed in the ovary, testis and uterus.Synonyms: Bcl-2-like protein 9, Bcl-2-related ovarian killer protein, Bcl2-L-9, Hbok
    基因ID
    29884
    NCBI登录号
    NP_059008
    UniProt
    Q792S6
    途径
    Positive Regulation of Endopeptidase Activity
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