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BOK 抗体

The 兔 多克隆 anti-BOK antibody is suitable to detect BOK in samples from 大鼠. It has been validated for WB.
产品编号 ABIN126989
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BOK 抗体 (ABIN126989)

抗原

See all BOK 抗体
BOK (BCL2-Related Ovarian Killer (BOK))

适用

  • 45
  • 15
  • 9
  • 1
  • 1
  • 1
大鼠

宿主

  • 43
  • 2

克隆类型

  • 44
  • 1
多克隆

标记

  • 25
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BOK antibody is un-conjugated

应用范围

  • 28
  • 26
  • 14
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 特异性

    This antibody reacts to Bok.

    纯化方法

    Affinity purified

    免疫原

    Synthetic peptide surrounding amino acid 44 of rat BOK.
  • 应用备注

    Western Blot: 0.5-4g/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原

    BOK (BCL2-Related Ovarian Killer (BOK))

    别名

    BOK / BCL2L9

    背景

    Bok (Bcl-2-related ovarian killer) is a pro-apoptotic Bcl-2 family protein identified in the ovary based on its dimerization with the anti-apoptotic protein Mcl-1. In addition to the Bcl-2 homology (BH) domains 1 and 2 and the transmembrane sequence, Bok also has a BH3 domain believed to be important for dimerization with selective anti-apoptotic Bcl-2 proteins and cell killing. Bok interacts strongly with some (Mcl-1, BHRF1, and Bfl-1) but not other (Bcl-2, Bcl-xL, and Bcl-w) anti-apoptotic members. In addition, cell killing induced by Bok was suppressed following coexpression with Mcl-1 and BHRF1, but not with Bcl-2, further indicating that Bok heterodimerized only with selective anti-apoptotic Bcl-2 proteins. Bok was highly expressed in the ovary, testis and uterus.Synonyms: Bcl-2-like protein 9, Bcl-2-related ovarian killer protein, Bcl2-L-9, Hbok

    基因ID

    29884

    NCBI登录号

    NP_059008

    UniProt

    Q792S6

    途径

    Positive Regulation of Endopeptidase Activity
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