CASP5 抗体
Our Local Distributor
北京 101111
Quick Overview for CASP5 抗体 (ABIN126975)
抗原
See all CASP5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- The affinity purified antibody preferentially detects the intermediate (32 kDa) and the fully (20 kDa) cleaved caspase-5.
-
纯化方法
- Immunoaffinity purified
-
免疫原
- Synthetic peptide surrounding amino acids 162 of human caspase-5
-
-
-
-
应用备注
-
Western Blot: 0.5-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 0.2 mg/mL
-
缓冲液
- PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA and 0.01 % thimerosal
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C/-80 °C
-
储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
-
-
- CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
-
别名
- Caspase-5
-
背景
- Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-5 is also known as Ich-3 and ICErel-III and can proteolytically processed by granzyme B. Over expression of caspase-5 induces apoptosis in Rat-1 and HeLa cells, which can be inhibited by CrmA and Bcl-2.Synonyms: CASP-5, CASP5, ICE(rel)-III, ICH-3 protease, ICH3, TY protease
-
基因ID
- 838
-
NCBI登录号
- NP_001129581
-
UniProt
- P51878
-
途径
- Inflammasome
抗原
-