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Caspase 3 抗体 (active, Cleavage Site, N-Term)

CASP3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN126957
发货至: 中国
  • 抗原 See all Caspase 3 (CASP3) 抗体
    Caspase 3 (CASP3)
    抗原表位
    • 19
    • 16
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 13
    • 13
    • 12
    • 11
    • 10
    • 9
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    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    active, Cleavage Site, N-Term
    适用
    • 272
    • 191
    • 147
    • 31
    • 17
    • 10
    • 9
    • 9
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 274
    • 39
    • 4
    • 2
    • 2
    克隆类型
    • 272
    • 48
    多克隆
    标记
    • 152
    • 26
    • 21
    • 14
    • 11
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    This Caspase 3 antibody is un-conjugated
    应用范围
    • 246
    • 108
    • 104
    • 85
    • 79
    • 65
    • 47
    • 35
    • 29
    • 28
    • 26
    • 19
    • 10
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The antibody preferentially recognizes the p17 fragment of the active caspase-3.
    纯化方法
    Affinity chromatography
    免疫原
    Synthetic peptide mapping to the N-terminus adjacent to the cleavage site of human caspase-3
    Top Product
    Discover our top product CASP3 Primary Antibody
  • 应用备注
    Western Blot: 0.5-4 μg/mL. Immunohistochemistry on paraffin sections: 10-20 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -20 °C to -70 °C.
  • 抗原
    Caspase 3 (CASP3)
    别名
    Caspase-3 (CASP3 产品)
    别名
    CPP32 antibody, CPP32B antibody, SCA-1 antibody, A830040C14Rik antibody, AC-3 antibody, Apopain antibody, CC3 antibody, Caspase-3 antibody, Lice antibody, Yama antibody, mldy antibody, xcpp32 antibody, casp3 antibody, zgc:100890 antibody, CASP-3 antibody, caspase-3 antibody, caspase 3 antibody, caspase 3 S homeolog antibody, caspase 3, apoptosis-related cysteine peptidase a antibody, caspase 3, apoptosis-related cysteine peptidase antibody, CASP3 antibody, Casp3 antibody, casp3.S antibody, casp3a antibody
    背景
    Caspase-3 has been extensively studied and implicated to play an important role in apoptosis. Active caspase-3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells (e.g., PARP). The affinity purified antibody recognizing the active forms of caspase-3 provides a new tool for identifying apoptotic cell populations in both tissue sections and cultured cells.Synonyms: Apopain, CASP-3, CASP3, CPP-32, CPP32, Cysteine protease CPP32, SCA-1, SCA1, SREBP cleavage activity 1, Yama protein
    基因ID
    836
    NCBI登录号
    NP_004337
    UniProt
    P42574
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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