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Caspase 3 抗体 (active, Cleavage Site, N-Term)

This 兔 多克隆 anti-Caspase 3 antibody specifically detects Caspase 3 in WB 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN126957
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Caspase 3 抗体 (active, Cleavage Site, N-Term) (ABIN126957)

抗原

See all Caspase 3 (CASP3) 抗体
Caspase 3 (CASP3)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Caspase 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    active, Cleavage Site, N-Term

    特异性

    The antibody preferentially recognizes the p17 fragment of the active caspase-3.

    纯化方法

    Affinity chromatography

    免疫原

    Synthetic peptide mapping to the N-terminus adjacent to the cleavage site of human caspase-3
  • 应用备注

    Western Blot: 0.5-4 μg/mL. Immunohistochemistry on paraffin sections: 10-20 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -20 °C to -70 °C.
  • 抗原

    Caspase 3 (CASP3)

    别名

    Caspase-3

    背景

    Caspase-3 has been extensively studied and implicated to play an important role in apoptosis. Active caspase-3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells (e.g., PARP). The affinity purified antibody recognizing the active forms of caspase-3 provides a new tool for identifying apoptotic cell populations in both tissue sections and cultured cells.Synonyms: Apopain, CASP-3, CASP3, CPP-32, CPP32, Cysteine protease CPP32, SCA-1, SCA1, SREBP cleavage activity 1, Yama protein

    基因ID

    836

    NCBI登录号

    NP_004337

    UniProt

    P42574

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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