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GZMB 抗体 (AA 7-227)

GZMB 适用: 人 WB, FACS, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal B18-1 unconjugated
产品编号 ABIN126926
发货至: 中国
  • 抗原 See all GZMB 抗体
    GZMB (Granzyme B (GZMB))
    抗原表位
    • 18
    • 16
    • 13
    • 10
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 7-227
    适用
    • 119
    • 49
    • 24
    • 10
    • 4
    • 2
    • 1
    • 1
    宿主
    • 80
    • 42
    • 1
    小鼠
    克隆类型
    • 76
    • 47
    单克隆
    标记
    • 77
    • 11
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GZMB antibody is un-conjugated
    应用范围
    • 70
    • 42
    • 37
    • 36
    • 18
    • 18
    • 17
    • 14
    • 13
    • 10
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Detects human Granzyme B.
    产品特性
    Synonyms: Granzyme-2, CGL1, CTSGL1, CSPB, CTLA1, CTLA-1, GRB, SECT, Fragmentin-2, T-cell serineprotease 1-3E, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Cathepsin G-like1
    纯化方法
    Affinity Purified
    免疫原
    Human recombinant granzyme B (aa 7-227)
    克隆位点
    B18-1
    亚型
    IgG1
    Top Product
    Discover our top product GZMB Primary Antibody
  • 应用备注
    Western Blot. Immunoprecipitation. Flow Cytometry. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 1 mg/mL BSA, 1.5 mM Sodium Azide and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at -20 °C to -70 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    GZMB (Granzyme B (GZMB))
    Abstract
    GZMB 产品
    别名
    CCPI antibody, CGL-1 antibody, CGL1 antibody, CSP-B antibody, CSPB antibody, CTLA1 antibody, CTSGL1 antibody, HLP antibody, SECT antibody, granzyme B antibody, GZMB antibody
    背景
    Granzyme B is a 27 kDa serine protease stored in granules of activated cytotoxic T cells and NK cells. Upon target cell contact, granzyme B is directionally exocytosed and assisted by perforin, enters the target cell. With its unique substrate specificity (granzyme B cleaves after Asp), granzyme B processes and activates various pro-caspases thereby inducing apoptosis in the target cell.Synonyms: CGL1, CSPB, CTLA-1, CTLA1, CTSGL1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRB, Granzyme-2, Lymphocyte protease, SECT, T-cell serine protease 1-3E
    基因ID
    3002
    UniProt
    P10144
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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