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GZMB 抗体 (AA 7-227)

This anti-GZMB antibody is a 小鼠 单克隆 antibody detecting GZMB in WB, FACS, IP, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN126926
发货至: 中国

Quick Overview for GZMB 抗体 (AA 7-227) (ABIN126926)

抗原

See all GZMB 抗体
GZMB (Granzyme B (GZMB))

适用

  • 178
  • 51
  • 26
  • 12
  • 4
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  • 1
  • 1

宿主

  • 94
  • 92
  • 2
小鼠

克隆类型

  • 101
  • 87
单克隆

标记

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  • 1
  • 1
  • 1
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  • 1
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This GZMB antibody is un-conjugated

应用范围

  • 91
  • 83
  • 44
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  • 17
  • 14
  • 13
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  • 9
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  • 1
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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

B18-1
  • 抗原表位

    • 53
    • 21
    • 16
    • 10
    • 10
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
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    • 1
    AA 7-227

    特异性

    Detects human Granzyme B.

    产品特性

    Synonyms: Granzyme-2, CGL1, CTSGL1, CSPB, CTLA1, CTLA-1, GRB, SECT, Fragmentin-2, T-cell serineprotease 1-3E, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Cathepsin G-like1

    纯化方法

    Affinity Purified

    免疫原

    Human recombinant granzyme B (aa 7-227)

    亚型

    IgG1
  • 应用备注

    Western Blot. Immunoprecipitation. Flow Cytometry. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 1 mg/mL BSA, 1.5 mM Sodium Azide and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the antibody undiluted (in aliquots) at -20 °C to -70 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    GZMB (Granzyme B (GZMB))

    背景

    Granzyme B is a 27 kDa serine protease stored in granules of activated cytotoxic T cells and NK cells. Upon target cell contact, granzyme B is directionally exocytosed and assisted by perforin, enters the target cell. With its unique substrate specificity (granzyme B cleaves after Asp), granzyme B processes and activates various pro-caspases thereby inducing apoptosis in the target cell.Synonyms: CGL1, CSPB, CTLA-1, CTLA1, CTSGL1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRB, Granzyme-2, Lymphocyte protease, SECT, T-cell serine protease 1-3E

    基因ID

    3002

    UniProt

    P10144

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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