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PTK2B 抗体 (pTyr402)

PTK2B 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 小鼠 Monoclonal 14F6 unconjugated
产品编号 ABIN126880
发货至: 中国
  • 抗原 See all PTK2B 抗体
    PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
    抗原表位
    • 24
    • 20
    • 17
    • 15
    • 10
    • 7
    • 6
    • 6
    • 6
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    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
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    pTyr402
    适用
    • 114
    • 113
    • 95
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 146
    • 12
    • 3
    小鼠
    克隆类型
    • 141
    • 20
    单克隆
    标记
    • 75
    • 11
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    This PTK2B antibody is un-conjugated
    应用范围
    • 123
    • 59
    • 44
    • 40
    • 39
    • 26
    • 13
    • 13
    • 9
    • 4
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody specifically interacts with activated Pyk2/CAKβ phosphorylated at tyrosine 402. The antibody does not crossreact with the non-phosphorylated form of Pyk2/CAKβ nor with unrelated phosphorylation sites.
    产品特性
    Synonyms: PYK2, RAFTK, Protein tyrosine kinase 2 beta, Focal adhesion kinase 2, CAK-beta, CADTK,Proline-rich tyrosine kinase 2, Cell adhesion kinase beta, Calcium-dependent tyrosinekinase, Related adhesion focal tyrosine kinase
    纯化方法
    Size exclusion chromatography
    免疫原
    Synthetic phosphopeptide conjugated to KLH
    克隆位点
    14F6
    亚型
    IgG1
    Top Product
    Discover our top product PTK2B Primary Antibody
  • 应用备注
    Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. ELISA: 0.05 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1 mL H2O (15 min, RT).
    缓冲液
    1 mL2 x PBS / 0.09 % Na-azide / PEG and Sucrose
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
    别名
    FAK2 / PTK2B (PTK2B 产品)
    别名
    CADTK antibody, CAKB antibody, FADK2 antibody, FAK2 antibody, PKB antibody, PTK antibody, PYK2 antibody, RAFTK antibody, CAKbeta antibody, E430023O05Rik antibody, Raftk antibody, Pyk2 antibody, fak1b antibody, ptk2.2 antibody, ptk2b antibody, si:ch1073-355e8.1 antibody, protein tyrosine kinase 2 beta antibody, PTK2 protein tyrosine kinase 2 beta antibody, protein tyrosine kinase 2aa antibody, PTK2B antibody, Ptk2b antibody, ptk2aa antibody
    背景
    Proline-rich tyrosine kinase 2 (Pyk2, also known as cellular adhesion kinase β, CAK β) is a 116 kDa cytoplasmic tyrosine kinase. Pyk2 is rapidely phosphorylated on tyrosine residues in response to activation by G-protein-coupled receptors as well as stress signals. Phosphorylation of Pyk2 leads to activation of stress-activated kinase 1 and 2 (SAPK1 and SAPK2).Synonyms: CADTK, CAK-beta, Calcium-dependent tyrosine kinase, Cell adhesion kinase beta, Focal adhesion kinase 2, PYK2, Proline-rich tyrosine kinase 2, Protein tyrosine kinase 2 beta, RAFTK, Related adhesion focal tyrosine kinase
    基因ID
    2185
    UniProt
    Q14289
    途径
    EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling
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