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GSK3 alpha 抗体 (pSer21)

GSK3a 适用: 人, 小鼠, 大鼠, 犬 WB, EIA 宿主: 小鼠 Monoclonal 9B8 unconjugated
产品编号 ABIN126804
发货至: 中国
  • 抗原 See all GSK3 alpha (GSK3a) 抗体
    GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
    抗原表位
    • 31
    • 15
    • 14
    • 14
    • 10
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer21
    适用
    • 96
    • 82
    • 64
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 110
    • 20
    • 2
    小鼠
    克隆类型
    • 108
    • 26
    单克隆
    标记
    • 74
    • 10
    • 9
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GSK3 alpha antibody is un-conjugated
    应用范围
    • 105
    • 60
    • 53
    • 19
    • 19
    • 15
    • 13
    • 13
    • 6
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody specifically recognizes GSK3alpha phosphorylated at serine 21 (Western blot: 51 kDa) but does not crossreact with the homologous phosphorylation site in GSK3beta (phospho-Ser 9).
    产品特性
    Synonyms: Glycogen synthase kinase-3 alpha, GSK3A, GSK-3 alpha, Factor A
    纯化方法
    Size exclusion chromatography
    组件
    incl. positive Control
    免疫原
    Synthetic phosphopeptide conjugated to KLH.
    克隆位点
    9B8
    亚型
    IgG1
    Top Product
    Discover our top product GSK3a Primary Antibody
  • 应用备注
    Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. ELISA: 0.0 5g/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1 mL H2O (15 min, RT).
    缓冲液
    1 mL2 x PBS / 0.09 % Na-azide / PEG and Sucrose
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
    别名
    GSK3 alpha (GSK3a 产品)
    别名
    2700086H06Rik antibody, GSK3A antibody, GSK-3[a] antibody, GSK-3[b] antibody, GSK3 antibody, gsk3a antibody, xgsk3 antibody, glycogen synthase kinase 3 alpha antibody, glycogen synthase kinase 3 alpha b antibody, glycogen synthase kinase 3 alpha S homeolog antibody, GSK3A antibody, Gsk3a antibody, gsk3a antibody, gsk3ab antibody, gsk3a.S antibody, Bm1_31380 antibody
    背景
    Glycogen Synthase Kinase 3 (GSK3) exists in two isoforms, alpha and beta (GSK3alpha, GSK3beta). GSK3 is an active kinase that becomes phosphorylated by PKB/akt upon growth factor stimulation. Phosphorylation of GSK3alpha at serine 21 or GSK3beta at serine 9, respectively, leads to inhibition of kinase activity of the GSK3.Synonyms: Factor A, GSK-3 alpha, GSK3A, Glycogen synthase kinase-3 alpha
    基因ID
    2931
    UniProt
    P49840
    途径
    PI3K-Akt Signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, Warburg Effect
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