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c-FOS 抗体 (N-Term)

c-Fos 适用: 人, 小鼠, 大鼠, 犬 WB, IHC (fro), EIA 宿主: 小鼠 Monoclonal 8B5 unconjugated
产品编号 ABIN126801
发货至: 中国
  • 抗原 See all c-FOS (c-Fos) 抗体
    c-FOS (c-Fos) (c-Fos)
    抗原表位
    • 26
    • 25
    • 21
    • 19
    • 18
    • 16
    • 15
    • 15
    • 9
    • 8
    • 4
    • 3
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    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    N-Term
    适用
    • 202
    • 154
    • 135
    • 12
    • 12
    • 11
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    人, 小鼠, 大鼠, 犬
    宿主
    • 193
    • 35
    • 8
    • 1
    小鼠
    克隆类型
    • 198
    • 38
    单克隆
    标记
    • 108
    • 14
    • 12
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    This c-FOS antibody is un-conjugated
    应用范围
    • 201
    • 80
    • 80
    • 76
    • 41
    • 34
    • 33
    • 25
    • 13
    • 12
    • 12
    • 5
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    This antibody specifically interacts with the N-terminus of c-Fos. The antibody is suitable for Western blot and ELISA applications. It can be used for the detection of cellular Fos levels that might dramatically change during signal transduction. It is an important tool in combination with mab Fos-34E4 (phospho-Ser374) for studying fos expression and phosphorylation.
    产品特性
    Synonyms: FOS, G0S7, Proto-oncogene protein c-fos, Cellular oncogene fos, G0/G1 switch regulatoryprotein 7
    纯化方法
    Subsequent Thiophilic Adsorption and Size Exclusion Chromatography.
    组件
    incl. positive Control
    免疫原
    Synthetic peptide conjugated to KLH.
    克隆位点
    8B5
    亚型
    IgG1
    Top Product
    Discover our top product c-Fos Primary Antibody
  • 应用备注
    Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. ELISA: 0.1 μg/mL (protein ELISA). Immunohistochemistry on frozen sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1 mL H2O (15 min, RT).
    缓冲液
    1 mL2 x PBS containing 0.09 % Sodium Azide, PEG and Sucrose
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
    Shelf life: one year from despatch
    有效期
    12 months
  • 抗原
    c-FOS (c-Fos) (c-Fos)
    别名
    C-Fos (c-Fos 产品)
    别名
    AP-1 antibody, C-FOS antibody, p55 antibody, c-fos antibody, D12Rfj1 antibody, cFos antibody, cFOS antibody, fos antibody, Fos proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene antibody, proto-oncogene c-Fos-like antibody, FOS antibody, Fos antibody, LOC101078177 antibody
    背景
    The immediated early gene product c-Fos is expressed following mitogenic stimulation. c-Fos functions as a sensor for MAPK signal duration. When MAPK activation is transient, MAPK activity declines before accumulation of the c-Fos protein. When MAPK activation is sustained, c-Fos is phosphorylated by MAPK at serine 374. Phosphorylation stabilizes the Fos protein and primes c-Fos for additional phosphorylation at threonine 325.Synonyms: Cellular oncogene fos, FOS, G0/G1 switch regulatory protein 7, G0S7, Proto-oncogene protein c-fos
    基因ID
    2353
    UniProt
    P01100
    途径
    S100 Proteins
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