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LYVE1 抗体 (AA 24-228) (Biotin)

This anti-LYVE1 antibody is a 兔 多克隆 antibody detecting LYVE1 in WB, FACS, IHC (p), EIA 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN126137
发货至: 中国
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Quick Overview for LYVE1 抗体 (AA 24-228) (Biotin) (ABIN126137)

抗原

See all LYVE1 抗体
LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This LYVE1 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 24-228

    特异性

    Highly specifc for Mouse Lyve-1.

    交叉反应 (详细)

    Species reactivity (tested):Mouse.

    纯化方法

    Antigen Affinity Chromatography

    免疫原

    Highly pure recombinant Mouse soluble LYVE-1 produced in insect cells (Cat.-No DA3524). Remarks: The recombinant soluble LYVE-1 consists of amino acid 24 (Ala) to 228 (Gly) and is fused to a C-terminal His-tag (6xHis).
  • 应用备注

    The unconjugated antibody can be used for ELISA (1-15 μg/mL), Western blotting (1-2 μg/mLwith the appropriate secondary reagents), FACS (3-20 μg/mL together with the appropriatesecondary reagents) and Cell sorting. The antibody is also suitable for Immunohistochemistry on on Paraffin as well as on FrozenSections (0.25-4 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with sterile water to a concentration of 0.1-1.0 μg/mL. Centrifuge vial prior to opening.

    缓冲液

    PBS, pH 7.4, 0.02 % Sodium Azide, 50x BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

    别名

    LYVE-1

    背景

    LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41 % similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 Molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 Molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.Synonyms: CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, LYVE1, Lymphatic vessel endothelial hyaluronic acid receptor 1, XLKD1

    基因ID

    114332

    NCBI登录号

    NP_444477

    UniProt

    Q8BHC0

    途径

    Glycosaminoglycan Metabolic Process
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