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CCR8 抗体

The 兔 多克隆 anti-CCR8 antibody (ABIN122580) specifically detects CCR8 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN122580
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CCR8 抗体 (ABIN122580)

抗原

See all CCR8 抗体
CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

适用

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宿主

  • 55
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克隆类型

  • 48
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多克隆

标记

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This CCR8 antibody is un-conjugated

应用范围

  • 49
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    Reacts with C-C Chemokine Receptor 8 (CCR8) (family: GPCR, subfamily: Chemokine)

    纯化方法

    Peptide immunogen affinity column

    免疫原

    Synthetic peptide - KLH conjugated
  • 应用备注

    Immunohistochemistry with formalin fixed paraffin embedded tissues: 28 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.7, containing 0.01 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-80 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

    别名

    CDw198 / CCR8

    背景

    CCR8, a Chemokine Receptor, binds the CC-chemokine I-309, which is secreted by umbilical vein endothelial cells. CCR8 also binds viral monocyte inflammatory protein-I (vMIP-I), which is induced by Kaposi sarcoma-related human herpesvirus-8. CCR8 induces endothelial chemotaxis and may function as an HIV-1 co-receptor on primary human cells, contributing to HIV-1-induced thymic pathogenesis. CCR8 expression has been reported in spleen and thymus, natural-killer cells, monocytes, and T cells, and at lower levels in peripheral blood leukocytes. Increased expression has been seen in allergen-challenged atopic asthma. No CCR8 expression was found in mesangial cells of the kidney cortex. ESTs have been isolated from human normal kidney, eye, and B cell/lung/testis libraries and from human brain, germ cell, and pancreas cancer libraries.Synonyms: C-C CKR-8, C-C chemokine receptor type 8, CC-CKR-8, CC-chemokine receptor CHEMR1, CCR-8, CKRL1, CMKBR8, CMKBRL2, Chemokine receptor-like 1, GPR-CY6, TER1

    基因ID

    1237

    UniProt

    P51685
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