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Metabotropic Glutamate Receptor 1 抗体 (Extracellular Domain)

GRM1 适用: 人, 大鼠, 小鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN122309
发货至: 中国
  • 抗原 See all Metabotropic Glutamate Receptor 1 (GRM1) 抗体
    Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
    抗原表位
    • 15
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain
    适用
    • 63
    • 43
    • 32
    • 15
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 75
    • 7
    • 2
    • 1
    克隆类型
    • 71
    • 14
    多克隆
    标记
    • 41
    • 6
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    • 2
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    • 1
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    This Metabotropic Glutamate Receptor 1 antibody is un-conjugated
    应用范围
    • 39
    • 30
    • 25
    • 15
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    • 9
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    • 2
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Reacts with Metabotropic Glutamate Receptor 1 (family: GPCR, subfamily: Metabotropic glutamate)
    纯化方法
    Peptide immunogen affinity column
    免疫原
    Synthetic peptide - KLH conjugated
    Top Product
    Discover our top product GRM1 Primary Antibody
  • 应用备注
    Immunohistochemistry with formalin fixed paraffin embedded tissues: 17 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS, pH 7.7, containing 0.01 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-80 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
    别名
    mGluR1a / GRM1a (GRM1 产品)
    别名
    fj39d05 antibody, wu:fj39d05 antibody, si:ch211-51a19.1 antibody, Glura antibody, mGlutR antibody, GB18621 antibody, GPRC1A antibody, MGLU1 antibody, MGLUR1 antibody, SCAR13 antibody, 4930455H15Rik antibody, ENSMUSG00000075319 antibody, Gm10828 antibody, Gprc1a antibody, mGluR1 antibody, nmf373 antibody, rcw antibody, wobl antibody, glutamate metabotropic receptor 1 antibody, glutamate receptor, metabotropic 1a antibody, metabotropic glutamate receptor 1 antibody, glutamate receptor, metabotropic 1 antibody, GRM1 antibody, grm1a antibody, mGlutR1 antibody, Grm1 antibody
    背景
    The Metabotropic Glutamate Receptor mGluR1 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. mGluR1 and mGluR5 are group I receptors that have been shown to activate phospholipase C. Alternative splice variants of the mGluR1 gene have been described, but their full-length nature has not been determined. Inflammation results in the activation of mGluR1 and mGluR5 in dorsal horn neurons of the spinal cord, leading to extracellular signal-regulated kinase (ERK) activation, which is required for nociceptive plasticity and enhanced pain. mGluR1 has been reported in various regions of the brain and spinal cord. ESTs have been isolated from brain and eye libraries. Caution: GLUR1 refers to Ionotropic Glutamate Receptor 1, not to Metabotropic Glutamate Receptor 1 (mGLUR1).Synonyms: Gprc1a, Metabotropic glutamate receptor 1, Mglur1
    UniProt
    Q13255
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