BDKRB1 抗体 (Cytoplasmic Domain)
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- 抗原 See all BDKRB1 抗体
- BDKRB1 (Bradykinin Receptor B1 (BDKRB1))
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抗原表位
- Cytoplasmic Domain
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BDKRB1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- Reacts with Bradykinin B1 Receptor 1 (family: GPCR, subfamily:Bradykinin)
- 交叉反应 （详细）
- Species reactivity (expected):Mouse and RatSpecies reactivity (tested):Human
- 纯化方法
- Immunoaffinity Chromatography.
- 免疫原
- Synthetic peptide - KLH conjugated
- Top Product
- Discover our top product BDKRB1 Primary Antibody
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anti-Bradykinin Receptor B1 (BDKRB1) (AA 1-100) antibody
BDKRB1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (AA 161-260) antibodyBDKRB1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (Cytoplasmic Domain) antibodyBDKRB1 适用: 人 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (Extracellular Domain) antibodyBDKRB1 适用: 人, 猴 IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (C-Term) antibodyBDKRB1 适用: 人, 猴 IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (AA 1-353) antibodyBDKRB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A2 unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (AA 1-353) antibodyBDKRB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (AA 1-353) antibodyBDKRB1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (Internal Region) antibodyVerified BDKRB1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Bradykinin Receptor B1 (BDKRB1) (AA 230-279) antibodyBDKRB1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry with formalin fixed paraffin embedded tissues: 5-9 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.09 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or(in aliquots) at -20 °C to -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- BDKRB1 (Bradykinin Receptor B1 (BDKRB1))
- 别名
- BDKRB1 (BDKRB1 产品)
- 背景
- Bradykinin Receptor B1 (BKB1) has been implicated in inflammation and nociception. BKB1 receptor is rapidly induced under many inflammatory conditions such as colitis and hyperalgesia, allergic rhinitis, and inflammation. In vitro studies have implicated lipopolysaccharide, interleukins, and interferon as effectors in the rapid induction of BKB1 receptor expression. BKB1 receptor-deficient mice are healthy, fertile, and normotensive but show blunted response to lipopolysaccharide-induced hypotension, reduced migration into inflamed tissues by polymorphonuclear leukocytes, and reduced activity-dependent facilitation of a spinal nociceptive reflex. Bradykinin B1 receptor is generally only minimally expressed under normal physiological conditions, but the expression is induced rapidly under pathologic conditions such as ischemia, atheromatous disease, or exposure to inflammatory cytokines. Expression has been reported in brain, colon, kidney, lung, nasal mucosa, pancreas, prostate, skin, spinal cord, and vessel. ESTs have been isolated from normal human connective tissue libraries and in human kidney and skin cancer libraries.Synonyms: B1 bradykinin receptor, B1R, BK-1 receptor, BKB1R, BKR1, BRADYB1, Bradykinin B1 Receptor
- 基因ID
- 623
- UniProt
- P46663
- 途径
- ACE Inhibitor Pathway
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