电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Serotonin Receptor 4 抗体 (Cytoplasmic Domain)

HTR4 适用: 人, 大鼠, 小鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN121987
发货至: 中国
  • 抗原 See all Serotonin Receptor 4 (HTR4) 抗体
    Serotonin Receptor 4 (HTR4)
    抗原表位
    • 15
    • 15
    • 13
    • 10
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cytoplasmic Domain
    适用
    • 61
    • 33
    • 32
    • 11
    • 10
    • 9
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    人, 大鼠, 小鼠
    宿主
    • 75
    • 1
    克隆类型
    • 75
    • 1
    多克隆
    标记
    • 29
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Serotonin Receptor 4 antibody is un-conjugated
    应用范围
    • 61
    • 27
    • 26
    • 26
    • 12
    • 9
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Reacts with 5-HT4 Receptor (family: GPCR, subfamily: Serotonin).
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    Synthetic peptide - KLH conjugated
    Top Product
    Discover our top product HTR4 Primary Antibody
  • 应用备注
    Immunohistochemistry with Formalin Fixed Paraffin Embedded Tissues: 6 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0 at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.09 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 to -70 °C forlonger. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    Serotonin Receptor 4 (HTR4)
    别名
    Serotonin Receptor 4 / HTR4 (HTR4 产品)
    别名
    5-HT4 antibody, 5-HT<4L> antibody, 5HTR4 antibody, 5-HT4S antibody, 5-HT4R antibody, 5 hydroxytryptamine (serotonin) receptor 4 antibody, 5-hydroxytryptamine receptor 4 antibody, Htr4 antibody, HTR4 antibody
    背景
    The 5-HT4 receptor, a member of the Serotonin Receptor subfamily, has been shown to affect the sensory and motor functions of the gut. Some of the most promising emerging therapies in Irritable Bowel Syndrome revolve around targeted pharmacotherapeutic modulation of serotonin receptors (ie, 5-HT3 and 5-HT4 subtypes). At least 9 isoforms (5-HT4A-5-HT4G, and 5-HT4n) have been described, which differ in the length and composition of their intracellular C termini after a common splicing site (L358). A ninth isoform (5-HT4H) results in the insertion of 14 amino acids into the second intracellular loop. 5-HT4 receptor expression has been documented primarily in the brain, and in colon, heart, and vessel. An EST has been isolated from a human cancerous nerve library. Ligand: Serotonin.Synonyms: 5-HT-4, 5-HT4, 5-hydroxytryptamine receptor 4
    基因ID
    3360
    UniProt
    Q13639
    途径
    JAK/STAT Signaling, cAMP Metabolic Process, S100 Proteins
You are here:
客服