Serotonin Receptor 2B 抗体 (N-Term)
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- 抗原 See all Serotonin Receptor 2B (HTR2B) 抗体
- Serotonin Receptor 2B (HTR2B)
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Serotonin Receptor 2B antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- Reacts with 5-HT2B receptor (Family GPCR, Subfamily: Serotonin).
- 纯化方法
- Peptide immunogen affinity chromatography
- 免疫原
- Synthetic peptide - KLH conjugated.
- Top Product
- Discover our top product HTR2B Primary Antibody
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anti-Serotonin Receptor 2B (HTR2B) (Internal Region) antibody
HTR2B 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 2B (HTR2B) (N-Term) antibodyHTR2B 适用: 人, Cow, 犬, 豚鼠, Pig, 马 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 2B (HTR2B) (AA 382-481) antibodyHTR2B 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 2B (HTR2B) antibodyHTR2B 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 2B (HTR2B) (AA 408-435), (C-Term) antibodyHTR2B 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB20470 unconjugated
anti-Serotonin Receptor 2B (HTR2B) (AA 1-56) antibodyHTR2B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Serotonin Receptor 2B (HTR2B) (AA 382-481) antibodyHTR2B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 2B (HTR2B) (AA 261-310) antibodyHTR2B 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 2B (HTR2B) (N-Term) antibodyHTR2B 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 2B (HTR2B) (AA 1-481) antibodyHTR2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemsiry on paraffin embedded sections (3 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.09 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody at 2-8 °C for up to one month or at -20 °C for longer. Avoid repeatedfreezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- Serotonin Receptor 2B (HTR2B)
- Abstract
- HTR2B 产品
- 背景
- 5-HT2B, a Serotonin Receptor, activates phospholipase C upon binding serotonin, which results in a rise in intracellular calcium. It is known that 5-HT2B regulates cardiovascular function during development and in adulthood, mice lacking functional 5-HT2B receptors died of heart defects during gestation or neonatally, and adult mutant mice displayed cardiopathy, including myocyte disarray and ventricular dilation. Abnormal vascular proliferation causes an increase in pulmonary blood pressure, which is associated with an increase in 5-HT2B receptor, resulting in the development of pulmonary hypertension. It has also been reported that the 5-HT2B is involved in cell-cycle regulation via interaction with tyrosine kinase pathways. 5-HT2B receptors may have a role in the initiation of migraine headaches, and selective antagonists may prove therapeutic in migraine treatment. 5-HT2B receptor is expressed in many tissues including human liver, kidney, lung, heart, pancreas, spleen, brain, spinal cord, gastrointestinal tract, placenta, and coronary and pulmonary arteries. It has also been reported in embryonic mouse heart and spinal cord. ESTs have been isolated from heart/melanocyte/uterus, kidney, prostate, skin, and thyroid libraries.Synonyms: 5-HT-2B, 5-HT2B, 5-hydroxytryptamine receptor 2B
- 基因ID
- 3357
- UniProt
- P41595
- 途径
- JAK/STAT Signaling, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
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