CXCR2 抗体 (N-Term)
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Quick Overview for CXCR2 抗体 (N-Term) (ABIN121966)
抗原
See all CXCR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts with CD182 / IL8RB at N-term. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except EYA3 (50 %).
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Immunoaffinity chromatography
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免疫原
- Synthetic petide - KLH conjugated.
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应用备注
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Immunohistochemistry on paraffin embedded sections: 4-16 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.09 % Sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-80 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
有效期
- 12 months
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- CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
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别名
- CD182 / IL8RB
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背景
- The IL8RB is a chemokine receptor also known as type 1 interleukin-8 receptor. There are three interleukin-8 receptors on chromosome 2: IL8RA (type 2), IL8RB (type 1), and a pseudogene. Results from mouse knock-out studies suggest that IL8RB may inhibit the expansion and development of neutrophils and B cells (Cacalano et al., 1994). IL8RB is a high-affinity receptor for IL8, and for GROalpha, beta, and gamma (Ahuja and Murphy, 1996). IL8RB has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.Synonyms: CDw128b, CXCR-2, CXCR2, GRO/MGSA receptor, IL-8 receptor type 2, IL8 receptor beta
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基因ID
- 3579
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UniProt
- P25025
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途径
- cAMP Metabolic Process
抗原
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