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CXCR2 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects CXCR2 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN121966
发货至: 中国
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Quick Overview for CXCR2 抗体 (N-Term) (ABIN121966)

抗原

See all CXCR2 抗体
CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

适用

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宿主

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克隆类型

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多克隆

标记

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This CXCR2 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
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    N-Term

    特异性

    This antibody reacts with CD182 / IL8RB at N-term. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except EYA3 (50 %).

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Immunoaffinity chromatography

    免疫原

    Synthetic petide - KLH conjugated.
  • 应用备注

    Immunohistochemistry on paraffin embedded sections: 4-16 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.09 % Sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-80 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.

    有效期

    12 months
  • 抗原

    CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

    别名

    CD182 / IL8RB

    背景

    The IL8RB is a chemokine receptor also known as type 1 interleukin-8 receptor. There are three interleukin-8 receptors on chromosome 2: IL8RA (type 2), IL8RB (type 1), and a pseudogene. Results from mouse knock-out studies suggest that IL8RB may inhibit the expansion and development of neutrophils and B cells (Cacalano et al., 1994). IL8RB is a high-affinity receptor for IL8, and for GROalpha, beta, and gamma (Ahuja and Murphy, 1996). IL8RB has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.Synonyms: CDw128b, CXCR-2, CXCR2, GRO/MGSA receptor, IL-8 receptor type 2, IL8 receptor beta

    基因ID

    3579

    UniProt

    P25025

    途径

    cAMP Metabolic Process
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