RNF216 抗体 (N-Term)
This anti-RNF216 antibody is a 兔 多克隆 antibody detecting RNF216 in WB 和 IHC (p). Suitable for 小鼠.
Quick Overview for RNF216 抗体 (N-Term) (ABIN121917)
抗原
See all RNF216 抗体
RNF216
(Ring Finger Protein 216 (RNF216))
适用
小鼠
宿主
兔
克隆类型
多克隆
标记
This RNF216 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- N-Term
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纯化方法
- Ion exchange chromatography
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anti-Ring Finger Protein 216 (RNF216) (N-Term) antibody
RNF216 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 216 (RNF216) (C-Term) antibodyRNF216 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline, 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- RNF216 (Ring Finger Protein 216 (RNF216))
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别名
- RNF216
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背景
- TRIAD3A is a ubiquitously expressed E3 ubiquitin-protein ligase which plays an important role in the innate immune response. Regulation of the level and duration of Toll-like receptor (TLR) activation is vital in controlling a pro-inflammatory response, to prevent harm to the host. Several proteins involved in the regulation of TLR signaling have been described including ST2 and IL-1R-associated kinase M, along with many other adaptor proteins of the MyD88 family, which mediate TLR signal transduction. TRIAD3A, identified as a RING finger member of the E3 ligase family of proteins, binds to the cytoplasmic tail of several TLRs, notably TLR4 and TLR9, resulting in ubiquitination and proteolytic degradation, thereby regulating their expression. TRIAD3A does not appear to regulate the expression of TLR2.Synonyms: E3 ubiquitin-protein ligase RNF216, RING finger protein 216, TRIAD3, Triad domain-containing protein 3, UBCE7IP1, Ubiquitin-conjugating enzyme 7-interacting protein 1, ZIN, Zinc finger protein inhibiting NF-kappa-B
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UniProt
- Q9NWF9
抗原
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