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GAPDH 抗体

GAPDH 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN121907
发货至: 中国
  • 抗原 See all GAPDH 抗体
    GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))
    适用
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    人, 小鼠, 大鼠
    宿主
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    克隆类型
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    多克隆
    标记
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    This GAPDH antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse and Rat
    纯化方法
    Affinity chromatography
    Top Product
    Discover our top product GAPDH Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, 0,02 % Sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))
    别名
    GAPDH (GAPDH 产品)
    背景
    GAPDH is a glycolytic enzyme which plays a key role in energy production, and has also been implicated in numerous cellular processes. GAPDH is a homotetramer molecule consisting of four 36 kDa subunits, constitutively expressed in most cells and tissues, and is responsible for the generation of energy during carbohydrate metabolism, catalysing the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate. The role of GAPDH as a multifunctional protein has emerged from many studies, confirming its involvement in critical nuclear pathways, apoptosis, membrane transport and fusion, DNA replication and repair and phosphotransferase activity. Furthermore, the ability of GAPDH to bind with high affinity to ß-amyloid precursor protein (Alzheimer's disease) and selectively with CAG mutated proteins, including huntingtin (Huntingdon's disease) and the androgen receptor (spinobulbar muscular atrophy), has focused many studies towards the role of GAPDH in the pathogenesis of neurodegenerative diseases (1).Synonyms: CDABP0047, GAPD, Glyceraldehyde-3-Phosphate Dehydrogenase
    UniProt
    P04406
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