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UBE2N 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects UBE2N in WB 和 IHC (p). It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN121903
发货至: 中国
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Quick Overview for UBE2N 抗体 (C-Term) (ABIN121903)

抗原

See all UBE2N 抗体
UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))

适用

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人, 大鼠, 小鼠

宿主

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  • 4
  • 2

克隆类型

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  • 23
多克隆

标记

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This UBE2N antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 5
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    • 2
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    C-Term

    纯化方法

    Ion exchange chromatography

    免疫原

    A 15 amino acid peptide located near the human UBC13 carboxy-terminus

    亚型

    IgG
  • 应用备注

    Western Blot: 0.5 μg/mL - 1 μg/mL, this antibody detects a band of approximately 16 kDa in human small intestine cell lystates. Immunohistochemistry on frozen sections: 2 μg/mL, this product requires antigen retrieval using heat treatment prior to staining of paraffin sections, sodium citrate buffer pH 6.0 is recommended for this purpose. Recommended Positive Control: Mouse thymus tissue.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.

    有效期

    12 months
  • 抗原

    UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))

    背景

    UBC13 is a 16 kDa enzyme which is an important component of the TLR (Toll-like receptor) and IL-1R signalling pathway. UBC13 is DNA-damage inducible protein which forms part of an enzyme complex, with UEV1A, that indirectly activates TAK1 via the ubiquitination of TRAF-6. Ubiquitin modification of proteins is important for error-free DNA repair and for targeting of short-lived or abnormal proteins for degradation.Synonyms: Bendless-like ubiquitin-conjugating enzyme, UBC13, Ubiquitin carrier protein N, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-protein ligase N

    UniProt

    P61088

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Positive Regulation of Response to DNA Damage Stimulus, Ubiquitin Proteasome Pathway
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