Caspase 7 抗体 (C-Term)
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Quick Overview for Caspase 7 抗体 (C-Term) (ABIN121893)
抗原
See all Caspase 7 (CASP7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody recognises an epitope within the C-terminal region (CT) of Caspase-7, a 35 kDa cysteine protease, otherwise known as ICE-like Apoptotic Protease 3 (ICE-LAP3) Caspase-7.
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纯化方法
- Affinity Chromatography
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免疫原
- A 16 amino acid peptide from human Caspase-7 carboxy-terminus
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亚型
- IgG
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anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-303) antibody
CASP7 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 207-303) antibodyCASP7 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-198) antibodyCASP7 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 29-198) antibodyCASP7 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4D10B2 unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-198) antibodyCASP7 适用: 人 WB, IHC, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-303) antibodyCASP7 适用: 人, 大鼠 WB, IHC, ELISA, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) antibodyCASP7 适用: 人, 小鼠, 大鼠, 猴, Pig, 犬, 兔, Hamster, 绵羊 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 7-1-11 unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (N-Term) antibodyCASP7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) antibodyKD Validated CASP7 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2090 unconjugated Recombinant Antibody
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 160-240) antibodyCASP7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1.0 μg/mL - 2.0 μg/mL. Immunohistochemistry on paraffin sections: 2.0 μg/mL, this product does not require protein digestion pre-treatment of paraffin sections eg. Trypsin or pronase prior to staing, this product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Recommended Positive Control: Skeletal muscle tissue.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
有效期
- 12 months
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- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
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别名
- Caspase-7
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背景
- ICE-LAP3 is a member of the ICE/Ced-3 subfamily, is an executioner caspase which undergoes proteolytic cleavage of its precursor to form active p12 and p20 subunits. Evidence that activation of Caspase-7 occurs during cell death induced by the cytokine death receptors Fas/APO-1 and the receptor of tumour necrosis factor (TNFR-1), coupled with the fact that granzyme-B activated Caspase-7 cleaves the nuclear enzyme poly (ADPribose) polymerase (PARP), suggests an important role for Caspase-7 in both cytokine-mediated and Granzyme-B mediated apoptosis pathways.Synonyms: Apoptotic protease Mch-3, CASP-7, CASP7, CMH-1, ICE-like apoptotic protease 3, MCH3
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UniProt
- P55210
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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